Recombinant production of lactoperoxidase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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435 6, 435 691, 4352523, 4353201, 435 221, 435 231, 435 232, 435 235, C12N 908, C12Q 168, C12P 2106, C07H 1900

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active

057563330

ABSTRACT:
Recombinant methods and materials useful in producing lactoperoxidases are disclosed. An illustrative form of lactoperoxidase is the bovine protein shown in FIG. 1. FIG. 1 also shows the DNA sequence natively encoding the bovine lactoperoxidase, including contiguous regions of the gene. Such DNAs are useful in a variety of applications including antisense technology, formation of triple helices, and performance of diagnostic assays.

REFERENCES:
patent: 4576817 (1986-03-01), Montgomery et al.
Mailliart, Pascal, Ph.D. Thesis Abstract entitled "Contribution to the valorization of bovine whey proteins: from purification to sequence analysis," University of Paris, (1989) 1 page total.
Kimura et al., "Human thyroid peroxidase: Complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs," Proc. Natl. Acad. Sci. (1987) 84:5555-5559.
Kimura et al, "cDNA-directed expression of human thyroid peroxidase," FEBS Letters (1989) 250(2):377-380.
Langbakk et al., "Lactoperoxidase from human colostrum," Biochem. J. (1989) 259:627-631.
Sievers, "Structure of Milk Lactoperoxidase: Evidence for a single polypeptide chain," FEBS Letters (1981) 127(2):253-256.
Glover, "The Principles of Cloning DNA," Gene Cloning, Chapman and Hall, New York, 1984, pp. 1-19.
Goff et al., "High Resolution Proton Nuclear Magnetic Resonance Spectroscopy of Lactoperoxidase," Biochem. Biophys. Res. Comm. (1985) 133:(2) 794-799.
Booth et al., "Bovine Myeloperoxidase and Lactoperoxidase Each Contain a High Affinity Site for Calcium," Biochem. Biophys. Res. Comm. (1989) 160(2) 897-902.
Carlstrom, "Physical and Compositional Investigations of the Subfractions of Lactoperoxidase," ACTA Chem. Scand. (1969) 23(1):185-202.
Paul et al., "The Chemical Structure of Lactoperoxidase," Immunol. Ser. (1983) 27:15-29.
Langbakk et al., "Demonstration and partial purification of lactoperoxidase from human colostrum," FEBS Letters (1984) 174(2):300-303.
Suggs et al., "Use of synthetic oligonucleotides as hybridization probes," Proc. Natl. Acad. Sci. (1981) 78(11) 6613-6616.
Carlstrom, "Lactoperoxidase: Some Spectral Properties of a Haemoprotein with a Prosthetic Group of Unknown Structure," ACTA Chem. Scand. (1969) 23:203-213.
Shindler et al., "Peroxidase from Human Cervical Mucus," Eur. J. Biochem. (1976) 65:325-331.
Tenovuo, "Different Molecular Forms of Human Salivary Lactoperoxidase," Archs. Oral Biol. (1981) 26:1051-1055.
Carlsson et al., "Hydrogen Peroxide Excretion by Oral Streptococci and Effect of Lactoperoxidase-Thiocyanate-Hydrogen Peroxide," Infect. & Immun. (1983) 40(1):70-80.
Carlstrom, "Lactoperoxidase: Identification of Multiple Molecular Forms and their Interrelationships," ACTA Chem. Scand. (1969) 23:171-184.
Ericsson et al., "Endogenous antibodies to bovine lactoperoxidase in children and adolescents," Allergy (1987) 42:430-433.
Gothefors et al., "Lactoperoxidase Activity in Human Milk and in Saliva of Newborn Infants," Infect. & Immun. (1975) 11(6):1210-1215.
Pfeil et al., "Lactoperoxidase consists of domains: a scanning calorimetric study," Biochem. Biophys. Acta (1986) 872:72-75.
Reiter et al., "An Evaluation of the Growth Promoting Effect of the Lactoperoxidase System in Newborn Calves," Anim. Prod. (1981) 32:297-306.
Rombauts et al., "Bovine Lactoperoxidase. Partial Characterization of the Further Purified Protein," Biochemistry (1967) 6(10):2965-2977.
Mailliart, Pascal On-Line Database, Ph.D. Thesis Abstract entitled "Contribution a la Valorisation des Proteines du Lactoserum de la Purification au Sequencage", University of Paris, (1989), 1 page total.
Kimura et al., Proc. Natl. Acad. Sci. (1987) 84:5555-5559.
Kimura et al., FEBS Letters (1989) 250(2):377-380.
Dull et al., DNA and Cell Biology (1990) 9(7):499-509.
Sievers "Structure of Milk Lactoperoxidase" FEBS Letters May, 1981 pp. 253-256.
Langbakk "Lactoperoxidase From Human Colostrum," Biochem J. (1989) 259: 627-631.
Glover "Principles of DNA Cloning" Gene Cloning 1984 pp. 1-19.
Lee et al. "Generation of cDNA Probes . . . " Science 239:1288-1291 (1988).
Green et al "The Role of Antisense RNA . . . " Ann Rev. Biochem. 1986 55:569-97.
Goff et al., Biochem. Biophys. Res. Comm. (1985) 133(2):794-799.
Langbakk et al., Biochem. J. (1989) 259:627-631.
Booth et al., Biochem. Biophys. Res. Comm. (1989) 160(2):897-902.
Carlstrom, ACTA Chem. Scand. (1969) 23(1):185-202.
Sievers et al., FEBS Letters (1981) 127(2):253-256.
Paul et al., Immunol. Ser. (1983) 27:15-29.
Langbakk et al., FEBS Letters (1984) 174(2):300-303.
Suggs et al., Proc. Natl. Acad. Sci. (1981) 78(11):6613-6616.
Carlsson et al., Infect & Immun. (1983) 40(1):70-80.
Carlstrom et al., ACTA Chem. Scand. (1969) 23:171-184.
Calstrom et al., ACTA Chem. Scand. (1969) 23:203-213.
Ericsson et al., Allergy (1987) 42:430-433.
Gothefors et al., Infect & Immun. (1975) 11(6):1210-1215.
Pfeil et al., Biochem. Biophys. Acta (1986) pp. 72-75.
Reiter et al., Anim. Prod. (1981) 32:297-306.
Rombauts et al., Biochemistry (1967) 6(10):2965-2977.
Shindler et al., Eur. J. Biochem. (1976) 65:325-331.
Tenovuo, Archs. Oral Biol. (1981) 26:1051-1055.

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