Recombinant procaryotic cell containing correctly processed huma

Details Recombinant procaryotic cell containing correctly processed huma Recombinant procaryotic cell containing correctly processed huma

1988-04-26

1989-08-22

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4351723, 43525234, 4352523, 530399, C12N 116, E12N 1500, C07K 1300

Patent

active

048596000

ABSTRACT:
The production of mature hGH in E coli and Pseudomonas strains transformed by a plasmid which encodes pre hGH (comprising the signal polypeptide and the hormone itself) is described. These prokaryotes process the pre-hGH to cleave the signal sequence and, thereby, produce mature hGH.

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