Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...
Patent
1995-12-01
1999-01-12
Knode, Marian C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant virus encoding one or more heterologous proteins...
4242051, 4242211, 4242351, 4241861, 4242041, 435 693, 435536, 435537, 536 2371, A61K 39215, A61K 39275, A61K 39285, C12N 701
Patent
active
058583734
ABSTRACT:
Attenuated recombinant viruses containing DNA encoding FIPV antigen(s) compositions thereof, as well as methods for making and using the compositions, expression products therefrom, and antibodies generated, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The compositions and products therefrom and antibodies generated have several preventive, therapeutic and diagnostic uses.
REFERENCES:
Vennema et al. "Primary Structure of the Membrane and Nucleocapsid Protein Genes of Feline Infectious Peritonitis Virus and Immunogenicity of Recombinant Vaccinia Viruses in Kittens". Virology. vol. 181:327-335, 1991.
Tartaglia et al. "NYVAC: A Highly Attenuated Strain of Vaccinia Virus". Virology. vol. 188:217-23, 1992.
Murphy et al. "Immunization against Viruses". Fields Virology. Raven Press. Field et al. Eds. Chapter 19, pp. 469-502/, 1990.
Gettig Russell
Paoletti Enzo
Frommer William S.
Knode Marian C.
Kowalski Thomas J.
Lee Datquan
Virogenetics Corporation
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