Recombinant PDGF A-chain homodimers and methods of use

Details Recombinant PDGF A-chain homodimers and methods of use Recombinant PDGF A-chain homodimers and methods of use

2005-09-06

2005-09-06

Saoud, Christine J. (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C530S399000, C435S069100, C435S320100, C435S325000

Reexamination Certificate

active

06939849

ABSTRACT:
DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.

REFERENCES:
patent: 4766073 (1988-08-01), Murray et al.
patent: 4769328 (1988-09-01), Murray et al.
patent: 4801542 (1989-01-01), Murray et al.
patent: 4845075 (1989-07-01), Murray et al.
patent: 4849407 (1989-07-01), Murray et al.
patent: 4889919 (1989-12-01), Murray et al.
patent: 5045633 (1991-09-01), Murray et al.
patent: 5128321 (1992-07-01), Murray et al.
patent: 5498600 (1996-03-01), Murray
patent: 6004929 (1999-12-01), Murray et al.
patent: 0177957 (1986-04-01), None
patent: 0 259 632 (1988-03-01), None
Johnnson et al.Biochem. Biophys Res Comm. 104(1) p. 66-74 (1982).
Antoniades et alScience220: p. 963-965 (1983).
Tong B. D., et al., “Cloning of the A-Chain of PDGF and A-Chain Expression in Human Endothelial Cells” (Abstract No. A 175)J. of Cellular Biochemistry(1987) p. 44.
Hoppe et al.,FEBS Letters(1987) 223 (2) :243-246.
Collins et al.,Nature(1985) 316:748-750.
Johnsson et al.,EMBO J.(1984) 3(5) :921-928.
Waterfield et al.,Nature(1983) 304:35-39.
Heldin et al.,Nature(1986) 319:511-514.
Betsholtz et al.,Nature(1986) 320:695-699.
Westermark et al.,Proc. Natl. Acad. Sci. USA(1986) 83:7197-7200.
Doolittle et al.,Science(1983) 221:275-277.
Gazit et al.,Cell(1984) 39:89-97.
Clarke et al.,Nature(1984) 308:464-467.
Kelly et al.,EMBO J.(1985) 4: (13A) :3399-3405.
Devare et al.,Cell(1984) 36:43-49.
Wang et al.,J. Biol. Chem.(1984) 259(17) :10645-10648.
Hannink et al.,Molecular and Cellular Biol.(1986) 6(4) :1343-1348.
Fry et al.,J. Cellular Physiol.(1986) 128:313-321.
Robbins et al.,Nature(1983) 305:605-608.
King et al.,Proc. Natl. Acad. Sci. USA(1985) 82:5295-5299.

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