Recombinant, non-glycosylated bpi protein and uses thereof

Details Recombinant, non-glycosylated bpi protein and uses thereof Recombinant, non-glycosylated bpi protein and uses thereof

1992-12-14

1994-08-02

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514021, A61K 3702, A61K 3514

Patent

active

053345843

ABSTRACT:
The present invention provides a method for preventing endotoxin-associated shock in a subject which comprises administering to the subject an amount of a BPI protein effective to bind to endotoxin so as to prevent endotoxin associated shock in the subject. This invention further provides a method for treating a subject suffering from endotoxin-associated shock which comprises administering to the subject an amount of a BPI protein effective to bind endotoxin so as to treat the subject suffering from endotoxin-associated shock.

REFERENCES:
patent: 5089274 (1992-02-01), Marra et al.
patent: 5171739 (1992-12-01), Scott
P. Elsbach, et al., (1988) Bacteria-Host Cell Interaction, pp. 47-60.
P. Gray, et al., (1988) Clinical Research, 36(3):620A.
J. Weiss, et al., (1982) The American Society of Clinical Investigation, Inc. 69:959.
J. Weiss, et al., (1985) The American Society of Clinical Investigation, Inc. 76:206.
J. Weiss, et al., (1982) Infection and Immunity, 38:1149-1153.
W. M. Shafer, et al., (1984) Infection and Immunity, 45:29-35.
C. J. Hovde, et al., (1986) Infection and Immunity, 54:142-148.
M. M. Farley et al., (1987) Infection and Immunity, 55:1536-1539.
G. I. Veld, et al., (1988) Infection and Immunity, 56:1203-1208.
M. M. Farley et al., (1988) Infection and Immunity, 56:1589-1592.
J. Weiss, et al., (1985) ASCI Metabolism, 33(2):567A.
C. E. Ooi, et al., (1987) J. Biol. Chem., vol. 262, No. 31, pp. 14891-14894 (Exhibit 3).

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