Recombinant myelomonocytic differentiation antigen CD14

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 696, 4352402, 4352523, 4353201, 536 235, 536 2431, C12N 1512, C12N 1585, C12N 1574, C12N 506

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055433030

ABSTRACT:
A recombinant myelomonocytic differentiation antigen CD14 has a primary amino acid sequence substantially equivalent to that of native human CD14. A process for isolating a DNA clone pCD-CD14 encoding CD14 comprises cell surface screening of COS 7 cells transfected with expressible DNA clones by monoclonal antibodies to CD14.

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Goyert, S. et al. (1986) "Biochemistry and expression of myelomonocytic antigens" J. Immunol. 137:3909-3914.
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Dimitriu-Bona, et al. (1983) "Human Mononuclear phagocyte differentiation antigens" J. Immunol. 130 145-152.
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Goyert, S. et al (1988) "The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors" Science 239:497-500.
Goyert, S & Ferrero E (1987) "Biochemical analysis of myeloid antigens and cDNA expression of GP55(cd 14)" in Leucocyte Typing III (eds) Michael, AJ., et al. Oxford University Press pp. 613-619.
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Haziot et al, "The Monocyte Differentiation Antigen, CD14 . . . " J. Immunol. 141(2):547-552 (Jul. 1988).
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