Recombinant MVA vaccinia virus

Details Recombinant MVA vaccinia virus Recombinant MVA vaccinia virus

1989-01-04

1993-02-09

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Lymphokine

424 88, 435 691, 435 693, 4351721, 4351722, 4351723, 4352351, 435236, 435239, 4352401, 4353201, 935 12, 935 32, 935 57, 935 65, A61K 3912, C12N 1500

Patent

active

051851466

ABSTRACT:
The present invention relates to recombinant vaccinia viruses which are derived from the modified virus Ankara (MVA) and which contain a DNA sequence which codes for a foreign antigen. The invention also relates to vaccines which contain a virus of this type in a form suitable for injection, as well as to a method for the preparation thereof. Furthermore, the invention relates to the use of a recombinant vaccinia virus MVA for the preparation of heterologous proteins in eukariotic cells.

REFERENCES:
patent: 4603112 (1986-07-01), Paoletti et al.
patent: 4722848 (1988-02-01), Paoletti et al.
patent: 4769330 (1988-09-01), Paoletti et al.
Smith et al., Biotechnology & Genetic Engineering Reviews, Russell, Ed. vol. 2 383-407, Oct. 1984.

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