Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-07
1997-10-21
Hutzell, Paula K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
4241841, 4242401, 4353201, 4352523, 435 693, C07H 2104, A61K 3900
Patent
active
056797842
ABSTRACT:
A recombinant plasmid comprises the cyaC and the cyaA genes of Bordetella which directs the expression of Bordetella, adenylate cyclase in a transformed host cell. A recombinant DNA molecule can comprise the Bordetella cyaA gene containing at least one insertion of a heterologous DNA sequence at at least one permissive site. In addition, a recombinant Bordetella adenylate cyclase comprises a heterologous epitope at a permissive site. Methods of inducing a specific B cell, helper T cell, and CTL cell immune response are provided.
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Ladant Daniel
Leclerc Claude
Sebo Peter
Ullmann Agnes
Hutzell Paula K.
Institut Pasteur
Prickril Benet
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