Recombinant mutant thrombin receptor and related pharmaceuticals

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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4352523, 4353201, 536 232, C12N 974, C12N 120, C07H 2104

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active

057982481

ABSTRACT:
Proteolytically inactive thrombin mutated at positions 43 and/or 99 and/or 205, whereby said mutation renders thrombin an antagonist of thrombin receptor.

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