Recombinant monoclonal antibodies

Details Recombinant monoclonal antibodies Recombinant monoclonal antibodies

1981-07-01

1984-10-02

Padgett, Benjamin R.

Chemistry: analytical and immunological testing

Involving production or treatment of antibody

436548, 436804, 436819, 260112R, 424 11, 424 85, 424177, 435 7, 435 29, 435 68, 4351723, 435240, 435948, C12N 1500, G01N 3354, G01N 3360, G01N 3376

Patent

active

044748930

ABSTRACT:
Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.

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