Recombinant methods and materials for producing epothilone...

Details Recombinant methods and materials for producing epothilone... Recombinant methods and materials for producing epothilone...

2006-10-31

2006-10-31

Nashed, Nashaat T. (Department: 1656)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C435S232000, C536S023200, C536S023100, C536S023700

Reexamination Certificate

active

07129071

ABSTRACT:
Recombinant nucleic acids that encode all or a portion of the epothilone polyketide synthase (PKS) are used to express recombinant PKS genes in host cells for the production of epothilones, epothilone derivatives, and polyketides that are useful as cancer chemotherapeutics, fungicides, and immunosuppressants.

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