Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-06-20
2000-04-11
Chan, Christina Y.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 696, 435328, 435332, 435335, C12N 1513, C12N 510, C12P 2108
Patent
active
060489723
ABSTRACT:
Monoclonal antibodies immunospecific for the neutrophil chemotactic factor, IL-8, have been humanized by reshaping the variable regions to conform more closely to human counterparts. These antibodies are useful in immunoassays to detect IL-8 and as ligands on immunoaffinity columns for purification of human IL-8. In addition, the humanized antibodies have an antiinflammatory effect in patients.
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Matsumoto Yoshihiro
Matsushima Kouji
Sato Koh
Tsuchiya Masayuki
Yamada Yoshiki
Chan Christina Y.
Chugai Pharmaceutical Co., Ltd.
Gambel Phillip
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