Recombinant Marek's disease virus, process for preparing the sam

Details Recombinant Marek's disease virus, process for preparing the sam Recombinant Marek's disease virus, process for preparing the sam

1994-07-07

1996-09-24

Mosher, Mary E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant virus encoding one or more heterologous proteins...

4242291, 4242141, 4352351, 4353201, 4351723, 935 32, 935 65, A61K 39295, A61K 3917, A61K 39255, C12N 701, C12N 1500

Patent

active

055588670

ABSTRACT:
A recombinant Marek's disease virus produced by the mutation of a Marek's disease virus with a plasmid wherein said plasmid comprises (1) a gene fragment derived from the Us region or inverted repeat sequences adjacent to both ends of said Us region of a Marek's disease virus genome and (2) an exogenous gene expression cassette incorporated in said gene fragment, said cassette comprising an exogenous gene bound downstream of a promoter derived from an animal cell or an animal virus, a process for preparing the same, a multivalent live vaccine for birds comprising the same, and a vector for administration of a physiologically active substance to birds which comprises the same.

REFERENCES:
patent: 5138033 (1992-08-01), Velicer et al.
patent: 5171677 (1992-12-01), Sakaguchi et al.
patent: 5231023 (1993-07-01), Morgan
patent: 5470734 (1995-11-01), Sondermeijer et al.
Ogawa et al Vaccine vol. 8 pp. 486-490 (1990).
Taylor et al J. Virol. vol. 64 pp. 1441-1450 (1990).
Sakaguchi et al Virus Genes vol. 6 pp. 365-378 (1992).
Cantello et al., "Isolation of a Marek's Disease Virus (MDV) Recombinant taining the LacZ Gene of Escherichia coli Stably Inserted within the MDV US2 Gene," J. of Virology, vol. 65, No. 3 (1991) pp. 1584-1588.
Igarashi et al., "Restriction Enzyme Map of Herpesvirus of Turkey DNA and Its Collinear Relationship with Marek's Disease Virus DNA," Virology, vol. 157, No. 2 (1987), pp. 351-358.
Fukuchi et al., "The Structure of Marek Disease Virus DNA: The Presence of Unique Expansion in Nonpathogenic Viral DNA," Proc. Natl. Acad. Sci. USA, vol. 82, No. 1, (1985), pp. 751-754.

Affiliated with

Also associated with

Rating

Recombinant Marek's disease virus, process for preparing the sam does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant Marek's disease virus, process for preparing the sam, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant Marek's disease virus, process for preparing the sam will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1927141