Recombinant Marek's disease virus and process for preparing the

Details Recombinant Marek's disease virus and process for preparing the Recombinant Marek's disease virus and process for preparing the

1989-09-08

1992-12-15

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4353201, C12N 1564, C12N 1586

Patent

active

051716771

ABSTRACT:
A recombinant Marek's disease virus which comprises a Marek's disease virus genom and a DNA fragment incorporated therein, said DNA fragment being constructed by incorporating a promoter derived from an animal cell or an animal virus and a structural gene coding for an exogenous protein into a gene fragment derived from a Marek's disease virus, a process for preparing the same which comprises preparing a gene fragment wherein a structural gene coding for an exogenous gene is linked to the downstream of a promoter derived from an animal cell or an animal virus, incorporating said gene fragment into a BamHI - H fragment of a gene of a Marek's disease virus type I, and incorporating said fragment into a Marek's disease virus type I genome, and a multivalent live vaccine for birds comprising the same.

REFERENCES:
Hirai et al, J. of General Virology 45: 119-131 (1979).
Nevis Fregien et al., "Activating Elements in the Promoter Region of the cken .beta.-actin Gene", Gene, vol. 48, pp. 1-11 (1986).
K. Fukuchi et al., "The Structure of Marek Disease Virus DNA: The Presence of Unique Expansion in Nonpathogenic Viral DNA", Proc. Natl. Acad. Sci., vol. 82, pp. 751-754, Feb. 1985.
Carol P. Gibbs et al., "Extensive Homology Exists Between Marek Disease Herpesvirus and its Vaccine Virus, Herpesvirus of Turkeys", Proc. Natl. Acad. Sci., vol. 81, pp. 3365-3369, Jun. 1984.
Chemical Abstracts, vol. 110, No. 17, Apr. 24, 1989, p. 231, Abstract No. 149170c.

Affiliated with

Also associated with

Rating

Recombinant Marek's disease virus and process for preparing the does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant Marek's disease virus and process for preparing the , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant Marek's disease virus and process for preparing the will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2092323