Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1997-02-28
2000-03-07
Stucker, Jeffrey
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4242051, 4242111, 4242121, 4242241, 424 936, 4352351, 435236, 4351721, C12N 1500, A61K 3912, A61K 39155, A61K 39165
Patent
active
060338865
ABSTRACT:
The present invention provides the generation of infectious replicating non-segmented negative-stranded RNA virus, entirely from cloned cDNA. This process offers the possibility to introduce mutations into the virus genome by means of recombinant DNA techniques.
REFERENCES:
patent: 5166057 (1992-11-01), Palese et al.
M.J. Schnell et al., The EMBO Journal, 13:18:4195-4203, 1994.
D. Eschle et al., "Retraction: Infectious Measles Virus from cloned cDNA," EMBO Journal, 10:11:3558, 1991.
K.K. Conzelmann et al., "Rescue of Synthetic Genome Analogs of Rabies Virus by Plasmid Encoded Proteins," J. Virol., 68:2:713-719, 1994.
W. Luytjes et al., "Amplification, Packaging and Expression of a Foreign gene by influenzy," Cell 59:6:1107-1113, 1989.
S. Li et al., "Chimeric Influenza Virus Induces Neutralising Antibodies," J. Virol., 67:12:6659-6666, 1993.
A. Pattnaik et al., "Cells that Express all Five Proteins from VSV from cloned cDNAs Support Replication, Assembly and Budding of Defective Interfering Particles," Proc. Natl. Acad. Sci. USA, 88:1379-1383, 1991.
I. Ballart et al., Infectious Measles Virus from Cloned cDNA, EMBO Journal, 9:379-384, 1990.
Metsikko K and Garoff H. Oligomers of the Cytoplasmic Domain of the p62/E2 Membrane Protein of Semliki Forest Virus Bind to the Nucleocapsid In Vitro J. Virol 64 (10) 4678-4683, Oct. 1990.
Luo L and Wagner R. Transcription Inhibition Site on the M Protein of Vesicular Stomatitis Virus Located by Marker Rescue of Mutant ts023(III) with M-Gene Expression Vectors J. Virol 63 (6)2841-2843, Jun. 1989.
Conzelmann K. Genetic Manipulation of non-segmented negative-strand RNA viruses J. Gen Virol. 77(3) 381-389, 1996.
Crowe J, Bui P, London W, Davis A, Hung P, Chanock R, and Murphy B. Satisfactorily attenuated and protective mutants derived from a partially attenuated cold-passaged respiratory syncytial virus mutant by introduction of additional attenuating mutations. Vaccine 12(8): 691-699, 1994.
Collins P, Mink M, and Stec, D. Rescue of synthetic analogs of respiratory syncytial virus genomic RNA and effect of truncations and mutations on the expression of a foreign reporter gene Proc. Nat'l Acad. Sci. 88 9663-9667, Nov. 1991.
Park K, Huang T, Correia F, and Krystal M. Rescue of a foreign by Sendai virus Proc. Nat'l Acad. Sci. 88 5537-5541, Jul. 1991.
Calain P, Curran J, Kolakofsky D, and Roux L. Molecular cloning of natural paramyxovirus copy-back defective interfering RNAs and their expression from DNA Virol. 191 62-71, 1992.
Pattnaik A, Ball L, LeGrone A, and Wertz G. Infectious Defective Interfering Particles of VSV from Transcripts of a cDNA Clone Cell 69:1011-1021, Jun. 1992.
Boyer J, Haenni A. Infectious transcripts and cDNA clones of RNA Viruses. Virology 198: 415-426, 1994.
Park Hankyel T.
Stucker Jeffrey
Sullivan Michael G.
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