Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1994-05-23
1997-01-14
Elliott, George C.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4353201, C12N 1500, C12N 1586
Patent
active
055938736
ABSTRACT:
The present invention provides recombinant infectious bovine rhinotracheitis (IBR) viruses useful in vaccines to protect bovines from infectious bovine rhinotracheitis and other bovine diseases. The present invention further provides methods for distinguishing an animal vaccinated with the vaccine of the present invention from an animal infected with a naturally-occurring IBR virus. The present invention also provides isolated DNA encoding the gpE glycoprotein of IBR virus and isolated DNA encoding the gpG glycoprotein of IBR virus.
REFERENCES:
patent: 4680176 (1987-07-01), Berns et al.
patent: 4703011 (1987-10-01), Kit et al.
patent: 4769331 (1988-09-01), Roizman et al.
patent: 4810634 (1989-03-01), Post et al.
patent: 4824667 (1989-04-01), Kit et al.
patent: 4877737 (1989-10-01), Shih et al.
patent: 5047237 (1991-09-01), Cochran
patent: 5068192 (1991-11-01), Cochran
patent: 5223424 (1993-06-01), Cochran et al.
R. W. Price and A. Khan. Resistance of Peripheral Autonomic Neurons to In Vivo Productive Infection by Herpes Simplex Virus Mutants Deficient In Thymidine Kinase Activity. Infection and Immunity 1981; 34: 571-580.
R. B. Tenser, et al. The Role of Pseudorabies Virus Thymidine Kinase Expression in Trigeminal Ganglion Infection. J. of General Virology 1983; 64: 1369-1373.
E. A. Petrovskis, et al. Deletions in Vaccine Strains of Pseudorabies Virus and Their Effect on Sythesis of Glycoprotein. J. of Virology 1986; 60; 1166-1169.
T. Ben-Porat, et al. Role of Glycoproteins of Pseudorabies Virus in Eliciting Neutralizing Antibodies. J. of Virology 1986; 154; 325-334.
D. R. Fitzpatrick et al. Expression of Bovine Herpesvirus 1 Glycoproteins gI and gIII in Transfected Murine Cells. J. of Virology 1988; 62: 4239-4248.
Federal Register, May 9, 1990; 55 No. 90; 19245-19253.
S. Kit et al. Gene-deleted IBRV Marker Vaccine. Veterinary Record 1990; 127: 363-364.
M. Shih et al. Expression of Hepatitis B Virus S Gene by Herpes Simplex Virus Type 1 Vectors Carrying the alpha and beta regulated Gene Chimeras. Proc. Natl. Acad. Sci. USA 1984; 81: 5867-5870.
S. J. Edwards et al. Plasmodium Falciparum Antigens in Recombinant HSV-1. Technological Advances in Vaccine Development 1988; 223-234.
J. P. Weir and P. R. Narayanan. The Use of B-galactosidase as a Marker Gene to Define the Regulatory Sequences of the Herpes Simplex Virus Type 1 Glycoprotein C Gene in Recombinant Herpesviruses. Nucleic Acids Research 1988; 16: 10267-10282.
R. R. Spaete and E. S. Mocarski. Insertion and Deletion Mutagenesis of the Human Cytomegalovirus Genome. Proc. Natl. Acad. Sci USA 1987; 84: 7213-7217.
R. C. Desrosiers et al. Synthesis of Bovine Growth Hormone in Primates by Using a Herpesvirus Vector. Molecular and Cellular Biology 1985; 5: 2796-2803.
D. R. Thomsen et al. Pseudorabies Virus as a Live Virus Vector for Expression of Foreign Genes. Gene 1987; 57: 261-265.
B. Moss. Vaccinia Virus: A Tool for Research and Vaccine Development. Science 1991; 252:1662-1667.
M. L. Cook and J. G. Stevens. Latent Herpetic Infections Following Experimetnal Viraemia. J. Gen. Virology. 1976; 31: 75-80.
R. W. Honess. Herpes Simplex and "The Herpes Complex": Diverse Observations And a Unifying Hypothesis. J. gen. Virol. 1984; 65: 2077-2107.
M. Kit, et al. Bovine Herpesvirus-1 (BHV-1)--Based viral Vector Which Expresses Foot and Mouth Disease Virus (FMDV) Epitopes on Surface of Virus Particles. Cold Spring Harbor Conference on Modern Approaches to New Vaccines including AIDS, Sep. 1990; p. 106.
U. V. Wirth, et al. Spatial and Temporal Distribution of Bovine Herpesvirus 1 Transcripts. J. of Virology 1989; 63:4882-4889.
J. M. Koomey, et al. Deletion of DNA Sequences in a Nononcogenic Variant of Herpesvirus saimiri. J. of Virology 1984; 50: 662-665.
F. Zuckerman, et al. Vaccination and Control of Aujeszky's Disease, "Role of Pseudorabies Virus Glycoproteins in Immune Response", J. T. van Oirschot (ed.). Kluwer Academic Publishers, London 1989; pp. 107-117.
R. L. Thompson, et al. Physical Location of a Herpes Simplex Virus Type-1 Gene Function(s) Specifically Associated with a 10 Million-Fold Increase In HSV Neurovirulence. Virology 1983; 131: 180-192.
K. Fukuchi, et al. The Structure of Marek Disease Virus DNA: The Presence of Unique Expansion in Nonpathogenic Viral DNA. Proc. Natl. Acad. Sci, USA 1985; 82: 751-754.
B. Lomniczi et al. Deletions in the Genomes of Pseudorabies Virus Vaccine Strains and Existence of Four Isomers of the Genomes. J. of Virology 1984; 49: 970-979.
B. Rooizman, et al. Bioengineering of Herpes Simplex Virus Variants for Potential Use as Live Vaccines. Cold Spring Harbor Conference on New Approaches to Viral Vaccines, Sep. 1983; 275-281.
Spaete et al., J. Virol., vol. 56, 1985, pp. 135-143.
Zijl et al., J. Gen. Virol., vol. 71, 1990, pp. 1747-1755.
Cochran Mark D.
MacDonald Richard D.
Elliott George C.
McKelvey Terry A.
PruTech Research and Development Partnership
Syntro Corporation
White John P.
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