Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2008-04-08
2008-04-08
Gambel, Phillip (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C424S133100, C530S391300, C530S387300, C530S388230
Reexamination Certificate
active
07354584
ABSTRACT:
The present invention provides novel antibodies that immunospecifically bind to an IL-9 polypeptide and compositions comprising said antibodies. The present invention also provides methods and compositions preventing, treating, managing, and/or ameliorating diseases and disorders associated with aberrant expression and/or activity of IL 9 or IL-9 receptor or subunits thereof, autoimmune diseases, inflammatory diseases, proliferative diseases, and infections comprising administration of one or more antibodies thereof that immunospecifically bind to an IL-9 polypeptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing these disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to an IL-9 polypeptide.
REFERENCES:
patent: 5149780 (1992-09-01), Plow et al.
patent: 5196511 (1993-03-01), Plow et al.
patent: 5204445 (1993-04-01), Plow et al.
patent: 5262520 (1993-11-01), Plow et al.
patent: 5306620 (1994-04-01), Ginsberg et al.
patent: 5478725 (1995-12-01), Lessey
patent: 5498694 (1996-03-01), Ruoslahti
patent: 5523209 (1996-06-01), Ginsberg et al.
patent: 5578704 (1996-11-01), Kim et al.
patent: 5589570 (1996-12-01), Tamura et al.
patent: 5652109 (1997-07-01), Kim et al.
patent: 5652110 (1997-07-01), Kim et al.
patent: 5693612 (1997-12-01), Jonczyk et al.
patent: 5705481 (1998-01-01), Jonczyk et al.
patent: 5753230 (1998-05-01), Brooks et al.
patent: 5767071 (1998-06-01), Palladino et al.
patent: 5770565 (1998-06-01), Cheng et al.
patent: 5780426 (1998-07-01), Palladino et al.
patent: 5817457 (1998-10-01), Bird et al.
patent: 5824307 (1998-10-01), Johnson
patent: 5830678 (1998-11-01), Carter
patent: 5849692 (1998-12-01), Jonczyk et al.
patent: 5955572 (1999-09-01), Ruoslahti et al.
patent: 5985278 (1999-11-01), Mitjans et al.
patent: 6005079 (1999-12-01), Casterman et al.
patent: 6048861 (2000-04-01), Askew et al.
patent: 6090944 (2000-07-01), Hutchinson
patent: 6096707 (2000-08-01), Heino et al.
patent: 6130231 (2000-10-01), Wityak et al.
patent: 6153628 (2000-11-01), Jin et al.
patent: 6160099 (2000-12-01), Jonak et al.
patent: 6171588 (2001-01-01), Carron et al.
patent: 6261559 (2001-07-01), Levitt et al.
patent: 6818216 (2004-11-01), Young et al.
patent: 2002/0051787 (2002-05-01), Prince et al.
patent: 2002/0168360 (2002-11-01), Dingivan et al.
patent: 2003/0091584 (2003-05-01), Young et al.
patent: 2003/0190311 (2003-10-01), Dall'Acqua et al.
patent: 2003/0219439 (2003-11-01), Reed et al.
patent: 2004/0005544 (2004-01-01), Fouchier et al.
patent: 2004/0018200 (2004-01-01), Oliver et al.
patent: 2004/0028685 (2004-02-01), Kinch et al.
patent: 2004/0091486 (2004-05-01), Carles-Kinch
patent: WO94/04678 (1994-03-01), None
patent: WO94/25591 (1994-11-01), None
patent: WO95/22543 (1995-08-01), None
patent: WO98/33919 (1998-08-01), None
patent: WO 00/78815 (2000-12-01), None
patent: WO 02/43660 (2002-06-01), None
patent: WO 02/069904 (2002-09-01), None
patent: WO 02/070007 (2002-09-01), None
patent: WO 02/098370 (2002-12-01), None
patent: WO 02/102974 (2002-12-01), None
patent: WO 03/075741 (2003-09-01), None
patent: WO 03/075957 (2003-09-01), None
patent: WO-2003-086458 (2003-10-01), None
patent: WO 03/094859 (2003-11-01), None
patent: WO 01/44301 (2004-06-01), None
patent: WO 04/091510 (2004-10-01), None
patent: WO 04/091519 (2004-10-01), None
Janeway et al., Immunobiology, 6th Ed., Garland Science, pp. 110-112 (2004).
Rudikoff, Proc Natl. Acad. Sci. USA 79: 1979-1983 (1982).
Liebman et al., Environmental Influences and Recognition in Enzyme Chemistry, VCH Publishers, p. 307, 1988.
ClinicalTrials.gov Identifer: NCT00394654, “A Study to Evaluate the Efficacy of MEDI-528 on Late Asthmatic Response With Atopic Asthma,” 4 pages as numbered by the Examiner, posted Feb. 2007 at www.clinicaltrials.gov.
U.S. Appl. No. 60/561,845, filed Apr. 12, 2004, Allan.
U.S. Appl. No. 60/477,801, filed Jun. 10, 2003, Reed.
U.S. Appl. No. 60/477,797, filed Jun. 10, 2003, Reed.
U.S. Appl. No. 60/462,307, filed Apr. 11, 2003, Reed.
U.S. Appl. No. 60/462,259, filed Apr. 11, 2003, Reed.
U.S. Appl. No. 60/398,475, filed Jul. 25, 2002, Young et al.
U.S. Appl. No. 60/388,921, filed Jun. 14, 2002, Oliver et al.
U.S. Appl. No. 60/388,920, filed Jun. 14, 2002, Oliver et al.
U.S. Appl. No. 60/379,368, filed May 10, 2002, Kinch et al.
U.S. Appl. No. 60/371,728, filed Apr. 12, 2002, Reed et al.
U.S. Appl. No. 60/371,683, filed Apr. 12, 2002, Reed et al.
U.S. Appl. No. 09/724,531, filed Nov. 28, 2000, Young et al.
GenBank Accession No. A60480.
GenBank Accession No. AAC17735.
GenBank Accession No. NM—000206.
GenBank Accession No. NM—002186.
GenBank Accession No. NM—176786.
GenBank Accession No. NM—000590.
GenBank Accession No. NP—000197.
GenBank Accession No. NP—000584.
GenBank Accession No. NP—002177.
GenBank Accession No. NP—789743.
Borrebaeck & Carlsson, 2001, “Human therapeutics antibodies.” Curr. Opin. in Pharm. 1:404-408.
Chowdhury & Wu., 2005, “Tailor- made antibody Therapeutics.” Methods 36:11-24.
Clackson et al., 1991, “Making antibody fragments using phage display libraries.” Nature 352:624-628.
Dall'Acqua et al., 1996, “A Mutational Analysis of the Binding of Two different proteins to the same antibody,” Biochem 35:9667-9676.
Dall'Acqua et al., 2005, “Antibody Humanization by framework shuffling” Methods 36:43-60.
Davies & Riechmann, 1995, “Antibody VH Domains as a Small Recognition Units.” Biotechnol. 13:475-479.
Dumoulin et al., 2002, “Single-domain antibody fragments with high conformational stability.” Protein Sci.11:500-515.
Holt, 2003, “Domain antibodies: proteins for therapy.” Trends in Biotech. 21(11):484-490.
Klimka et al., 2000, “Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.” Brit. J. of Canc. 83(2):252-260.
Kobayashi et al., 1997, “Analysis of Assembly of Synthetic Antibody Fragments: Expression of Functional scFV with Predefined Specificity.” Biotechniques 23:500-503.
Malmborg et al., 1995, “BIAcore as a tool in antibody engineering.” J. of Immunol. Methods. 183:7-13.
Marks et al., 1992, “By-Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling.” Biotechnol. 10:779-783.
Muyldermans, 2001, “Single domain camel antibodies: current status.” J. Biotechnol. 74(4):277-302.
Nuttal et al., 2000, “Immunoglobulin VH domains and beyond: design and selection of single-domain binding and targeting reagents.” Curr. Pharm. Biotechnol. 1(3):253-263.
Ohlin & Borrebaeck, 1998, “Insertions and deletions in hypervariable loops of antibody heavy chains contribute to molecular diversity.” Molec. Immunol. 35:233-238.
Pereira et al., 1998, “Cardiolipin Binding a Light Chain from Lupus-Prone Mice.” Biochem. 37:1430-1437.
Rader et al., 1998, “A phage display approach for rapid antibody humanization: Designed combinatorial V gene libraries.” Proc. Natl. Acad. Sci. USA 95:8910-8915.
Riechmann et al., 1999, “Single domain antibodies: comparison of camel VH and camelised human VH domains.” J. Immuno. Methods 231:25-38.
Soderlind et al., 1995, “Domain libraries: Synthetic diversity for de novo design of antibody V-regions.” Gene 160:269-272.
Soderlind et al., 2001, “The Immune Diversity in a Test Tube—Non-Immunised Antibody Libraries and Functional Variability in Defined Protein Scaffolds.” Combinator. Chem. & High Through. Screen. 4:409-416.
Tusmoto et al., 2002, “Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determing regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.” FEBS Letters 525:77-82.
Van Den Beucken et al., 2001, “Bui
Davies Julian
Reed Jennifer Lynne
Tang Ying
Watkins Jeffry D.
Wu Herren
Gambel Phillip
MedImmune, Inc.
Skelding Zachary
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