Recombinant IL-5 antagonists useful in treatment of IL-5 mediate

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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435328, 435335, 5303873, 53038823, A61K 39395, C12P 2108, C07K 1600

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active

056933231

ABSTRACT:
Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.

REFERENCES:
patent: 5096704 (1992-03-01), Coffman et al.
Collet et al., PNAS USA 89: 10026-10030, 1992.
Clark et al. in:"Enzyme Immunoassay", Maggio Ed., CRC Press 1980, pp. 167-179.
Kabat, "Sequences of Proteins of Immunological Interest", NIN PUBL No. 91-3242, 1991 pp. 128, 318.

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