Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-08-15
2006-08-15
Kemmerer, Elizabeth (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120, C435S069100, C435S252300, C435S320100, C424S009100, C424S009200, C436S501000, C530S350000, C536S023500
Reexamination Certificate
active
07090989
ABSTRACT:
Transformed cells designed to express a recombinant human SMBP at an elevated level to the extent that its ligand-binding activity can be measured, and cellular membrane fractions thereof; recombinant human SMBPs isolated from the transformed cells or the cellular membrane fractions thereof; a screening system for human SMBP agonists/antagonists characterized by utilizing the transformed cells, the cellular membrane fractions thereof or the isolated recombinant human SMBPs; and human SMBP agonists or antagonists obtainable by the screening system, are provided by deleting the polythymidine sequence from the base sequence of the 3′-untranslated region.
REFERENCES:
patent: WO 9826065 (1998-06-01), None
Sugasawa, Toshinari et al., The Journal of Biological Chemistry, vol. 272, No. 34, pp. 21244-21252. (1997).
Sambrook et al., Molecular Cloning, pp. 8.11-8.30, (1989).
Myer et al., EMBO J., vol. 16, No. 8 pp. 2130-2139, (1997).
Bonin et al., Gene, vol. 14, pp. 75-77, (1994).
Hidaka Jun
Sugasawa Toshinari
Birch & Stewart Kolasch & Birch, LLP
Brannock Michael
Dainippon Sumitomo Pharma Co. ,Ltd.
Kemmerer Elizabeth
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