Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1995-06-07
1999-01-19
Ulm, John
Drug, bio-affecting and body treating compositions
Lymphokine
530351, 930140, 930145, A61K 3819, C07K 1453
Patent
active
058611509
ABSTRACT:
The present invention is directed to a biologically active CSF-1 dimer comprising a first CSF-1 monomer and a second CSF-1 monomer, wherein at least one of the monomers is truncated at the C-terminus after residue position 223. The dimers also include point mutations in one or both of the CSF-1 monomer. The invention also includes pharmaceutical compositions that comprise the CSF-1 dimer in a pharmaceutical excipient.
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Cowgill Cynthia
Halenbeck Robert
Koths Kirston
Laird Walter J.
Blackburn Robert P.
Chiron Corporation
Pochopien Donald
Potter James E. R.
Saoud Christine
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