Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-07-13
1997-03-04
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 43525233, 5303873, 53038835, 4241331, 4241601, 4241481, C12P 2108, C07K 1610, A01K 3942, C12N 1513
Patent
active
056078471
ABSTRACT:
The present invention provides human monoclonal antibodies, derived from the murine mAb NM-01 (PCT/US92/07111), which are specifically reactive with HIV gp120 and have the capacity to neutralize the infection of H9 cells in culture by live HIV-1 strains MN and III.sub.B as shown by reverse transcriptase, p24 and syncytium formation assays. These antibodies were shown to be as or more effective than the parent murine antibody by the aforementioned criteria.
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Armour Kathryn L.
Carr Francis J.
Harris William J.
Nissin Shokuhin Kabushiki Kaisha
Nucker Christine M.
Reeves Julie E.
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