Recombinant HTLV-III proteins and uses thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 71, 422 56, 436504, 530350, C12Q 170, C12Q 100, G01N 33567, C07K 500

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active

052623017

ABSTRACT:
Novel recombinant HTLV-III fusion proteins denoted R10, RB1, 590 and the HIV portion of each of these proteins are useful in the diagnosis, prophylaxis or therapy of AIDS. Protein R10 is a 95 kD fusion protein; protein PB1 is a 26 kD fusion protein and protein 590 is an 86 kD fusion protein.

REFERENCES:
patent: 4520113 (1985-05-01), Gallo et al.
Chang, et al., 1985, "Expression in Escherichia coli of Open . . . " Science 228: 93-96.
Crowl, et al., 1985, "HTLV-III Env Gene Products Synthesize of E. coli . . . " Cell 41: 979-986.

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