Recombinant host for producing L-asparaginase II

Details Recombinant host for producing L-asparaginase II Recombinant host for producing L-asparaginase II

2007-06-08

2010-10-05

Ramirez, Delia M (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S252330, C435S320100, C435S069100, C435S018000, C536S023200, C530S350000

Reexamination Certificate

active

07807436

ABSTRACT:
The invention provides a recombinantEscherichia colihost cell for producing anEscherichia coli-asparaginase II enzyme. The host cell includes anEscherichia colichromosome and at least one copy of a recombinant extrachromosomal vector, wherein the recombinant extrachromosomal vector encodes the L-asparaginase II enzyme, wherein the host cell chromosome also encodes the same L-asparaginase II enzyme, and wherein the host chromosome does not encode any other isoform of L-asparaginase II.

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