Recombinant herpes simplex viruses vaccines and methods

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4242311, 4241861, 4352351, 435236, 536 2372, A61K 39245, C12N 704, C12N 700

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active

06120773&

ABSTRACT:
A recombinant herpes simplex virus genome having modified .gamma..sub.1 34.5 genes incapable of expressing an active ICP34.5 gene product, vaccines comprising the recombinant herpes simplex virus genome methods for immunizing a host against the herpes simplex virus using the recombinant herpes simplex virus genome, and a method for preparing the vaccine are disclosed.

REFERENCES:
patent: 4769331 (1988-09-01), Roizman et al.
patent: 4859587 (1989-08-01), Roizman et al.
patent: 4999296 (1991-03-01), Kit et al.
patent: 5068192 (1991-11-01), Cochran
patent: 5238688 (1993-08-01), Roizman
Location and Orientation of Homologous Sequences in the Genomes of Five Herpesviruses by A.J. Davison and N.M. Wilkie, J. gen. Virol. (1983), 64, 1927-1942.
MacLean et al, J. Gen. Virol. 72: 2305-2310, 1991.
Thompson et al, Microb Pathog 1: 409-16 (abstract only cited), Aug. 1986.
Thompson et al, Virology 172: 435-450, 1989.
Ackermann et al., J. Virol., 58(3), 843-850 (1986).
Braun et al., J. Virol., 46, 103-112 (1983).
Brown et al., J. Gen. Virol., 18, 329-346 (1973).
Centifanto-Fitzgerald et al., J. Exp. Med., 155, 475-489 (1982).
Chou et al., Cell, 41, 803-811 (1985).
Chou et al., J. Virol., 57(2), 629-637 (1986).
Chou et al., J. Virol., 64(3), 1014-1020 (1990).
Deiss et al., J. Virol., 59 605-618 (1986).
Ejercito et al., J. Gen. Virol., 2, 357-364 (1968).
Field et al., J. Hygiene, 81, 267-277 (1978).
Fields et al., Eds., Fundamental Virology, Chap. 10, 161-163 (1986).
Fields et al., Eds., Field's Virology, Chap. 66, 1843-1887 (1990).
Hammer et al., J. Infect. Dis., 141(4), 436-440 (1980).
Hayward et al., Proc. Natl. Acad. Sci. (USA), 72(11), 4243-4247 (1975).
Honess et al., J. Virol., 12, 1347-1365 (1973).
Hubenthal-Voss et al., J. Virol., 62, 454-462 (1988).
Javier et al., J. Virol., 61(6), 1978-1984 (1987).
Kieff et al., J. Virol., 8, 125-132 (1971).
Larder et al., J. Gen. Virol., 67, 2501-2506 (1986).
Linnemann et al., Lancet, i. 964-966 (1978).
McGeoch et al., J. Gen. Virol., 69, 1531-1574 (1988).
McGeoch et al., Nucleic Acids Res., 14, 1727-1745 (1986).
Meignier et al., J. Infect. Diseases, 158(3), 602-614 (1988).
Meignier et al., Vaccines 87, Cold Spring Harbor Laboratory, 368-373 (1987).
Meignier et al., Virology, 162, 251-254 (1988).
Mocarski et al., Cell, 31, 89-97 (1982).
Mocarski et al., Proc. Natl. Acad. Sci. (USA), 78, 7047 (1981).
Morse et al., J. Virol., 26(2), 389-410 (1978).
Perry et al., J. Gen. Virol., 67, 2365-2380 (1986).
Perry et al., J. Gen Virol., 69, 2831-2846 (1988).
Poffenberger et al., J. Virol., 53(2), 587-595 (1985).
Poffenberger et al., Proc. Natl. Acad. Sci. (USA), 80, 2690-2694 (1983).
Post et al., Cell, 25, 227-232 (1981).
Post et al., Proc. Natl. Acad. Sci. (USA), 77(7), 4201-4205 (1980).
Sanger et al., Proc. Natl. Acad. Sci. (USA), 74, 5463-5467 (1977).
Sheldrick et al., Cold Spring Harbor Symp. Quant. Biol., 39, 667-678 (1975).
Stevens et al., J. Exp. Medicine, 133, 19-38 (1971).
Taha et al., J. Gen. Virol., 70, 705-716 (1989).
Taha et al., J. Gen. Virol., 70, 3073-3078 (1989).
Thompson et al., J. Virol., 55(2), 504-508 (1985).
Thompson et al., J. Virol., 58(1), 203-211 (1986).
Thompson et al., Virology, 131, 171-179 (1983).
Thompson et al., Virology, 131, 180-192 (1983).
Thompson et al., Virology, 172, 435-450 (1989).
Varmuza et al., Cell, 41, 793-802 (1985).
Vlazny et al., Proc. Natl. Acad. Sci. (USA), 79, 1423-1427 (1982).
Wadsworth et al., J. Virol., 15(6), 1487-1497 (1975).
Warren et al., NEJM, 298:1068-1070 (1978).
Civil Complaint filed Jul. 8, 1999 in the United States District Court for the Northern District of Illionis Eastern Division; Joany Chou (Plaintiff) v. The University of Chicago, Arch Development Corporation, Bernard Roizman and Aviron Company (Defendants); Civil Action No. 99C 4495.

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