Recombinant fibronectin-based extracellular matrix for wound hea

Details Recombinant fibronectin-based extracellular matrix for wound hea Recombinant fibronectin-based extracellular matrix for wound hea

1998-02-18

1999-09-28

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514950, 514969, 530300, 530350, 530810, 530812, A01N 3718, A61K 3800, C07K 100

Patent

active

059588748

ABSTRACT:
The invention provides an extracellular matrix for enhancing wound healing. The extracellular matrix comprises a recombinant fibronectin protein and a backbone matrix, wherein the recombinant fibronectin protein comprises peptides from two or more fibronectin domains. The extracellular matrix facilitates wound healing by providing hemostasis and, in addition, an environment that intrinsically recruits new tissue cells to the wound site. The extracellular matrix according to the subject invention is thus used in a method for enhancing wound healing. The method comprises applying the extracellular matrix to the wound.

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