Recombinant feline herpesvirus vaccine

Details Recombinant feline herpesvirus vaccine Recombinant feline herpesvirus vaccine

1996-06-19

1997-07-29

Nucker, Christine M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4352351, 435236, 435351, 4241841, 4241991, 4242291, 4242051, 536 2372, 536 241, A61K 3912, A61K 39245

Patent

active

056521197

ABSTRACT:
The present invention is concerned with a Feline herpesvirus (FHV) mutant comprising a heterologous gene introduced into an insertion-region of the FHV genome.
The invention also relates to a vector vaccine comprising such an FHV mutant which expresses a heterologous polypeptide derived from a feline pathogen and induces an adequate immune response in an inoculated host against both FHV and the feline pathogen.

REFERENCES:
Grail et al., Arch. Virol (1991) 116: 209-220.
P.A. Rota et al., "Physical Characterization of the Genome of Feline Herpesvirus-1," Virology, vol. 154, No. 1, pp. 168-179, Oct. 15, 1986, New York, USA.
G.E. Cole et al., "Recombinant Feline Herpesvirus is Expressing Feline Leukimia Virus Envelope and Gag Proteins," Journal of Virology, vol. 64 No. 10, pp. 4930-4938, Oct. 1990.
L. Nicholson et al., "The Nucleotide Sequnece of the Equine Herpesvirus 4 gC Gene Homologue," Virology, vol. 179, No. 1, pp. 378-387, Nov. 1990, NY.
G.P. Allen et al., "Characterization of an Equine Herpesvirus Type 1 Gene Encoding a Glycoprotein (gp13) with Homology to HSV Glycoprotein C," Journal of Virology, vol. 62, No. 8, pp. 2850-2858, Aug. 1988.

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