Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2007-10-10
2010-02-09
Stucker, Jeffrey (Department: 1648)
Chemistry: molecular biology and microbiology
Vector, per se
C435S091400, C435S091420, C424S229100
Reexamination Certificate
active
07659114
ABSTRACT:
An attenuated feline recombinant herpesvirus 1 (FHV-1), which is prepared by identifying gene regions in the genome wherein inserted foreign genes can be expressed without affecting the replication of FHV-1 and has least two types of foreign nucleic acid sequences inserted thereinto, usable as a vector virus or a vaccine. In this attenuated recombinant FHV-1, at least two types of foreign genes are inserted in such a manner as allowing the expression into two different gene regions exerting no lethal effect on the proliferation of the virus in the feline herpesvirus 1 genome.
REFERENCES:
patent: 6074649 (2000-06-01), Audonnet et al.
patent: 0576092 (2003-12-01), None
patent: 09-000267 (1997-07-01), None
patent: WO 90/01547 (1990-02-01), None
patent: WO 94/03621 (1994-02-01), None
patent: WO 95/00172 (1995-01-01), None
patent: WO 97/20059 (1997-06-01), None
patent: WO 98/50069 (1998-11-01), None
animalclinic.com/FELVEASY.htm.
Eiji Sato et al. “Efficient expression of the envelope protein of feline immunodeficiency virus in a recombinant feline herpesvirus type 1 (FHV-1) using the gC promoter of FHV-1”, Virus Research, Sep. 2000, p. 13-23, vol. 70, No. 1-2.
N. Yokoyama et al., “Pathogenicity and vaccine efficacy of a thymidine kinase-deficient mutant of feline herpesvirus type 1 in cats”, Archives of Virology, 1996, p. 481-494, vol. 141.
N. Yokoyama et al., “Vaccine efficacy of recombinant feline herpesvirus type 1 expressing immunogenic proteins of feline calicivirus in cats”, Archives of Virology, 1996, p. 2339-2351, vol. 141.
Jack H. Nunberg et al., “Identification of the Thymidine Kinase Gene of Feline Herpesvirus: Use of Degenerate Oligonucleotides in the Polymerase Chain Reaction To Isolate Herpesvirus Gene Homologs”, Journal of Virology, Aug. 1989, p. 3240-3249, vol. 63, No. 8.
Naoaki Yokoyama et al., “Construction of the Recombinant Feline Herpesvirus Type 1 Deleted Thymidine Kinase Gene”, J. Vet. Med. Sci., 1995, p. 709-714, vol. 57, No. 4.
Georgette E. Cole et al., “Recombinant Feline Herpesviruses Expressing Feline Leukemia Virus Envelope and gag Proteins”, Journal of Virology, Oct. 1990, p. 4930-4938, vol. 64, No. 10.
Richard C. Wardley et al., “The use of feline herpesvirus and baculovirus as vaccine vectors for the gag and env genes of feline leukaemia virus”, Journal of General Virology, 1992, p. 1811-1818, vol. 73, Printed in Great Britain.
Marja J. Willemse et al., “The gene downstream of the gC homologue in feline herpes virus type 1 is involved in the expression of virulence”, Journal of General Virology, 1994, p. 3107-3116, vol. 75, Printed in Great Britain.
Marja J. Willemse et al., “In vivo properties of a feline herpesvirus type 1 mutant carrying a lacZ insertion at the gl locus of the unique short segment”, Vaccine, 1996, p. 1-5, vol. 14, No. 1, Elsevier Science Ltd., Printed in Great Britain.
Michael D. Sussman et al., “A Feline Herpesvirus-1 Recombinant with a Deletion in the Genes for Glycoproteins gl and gE Is Effective as a Vaccine for Feline Rhinotracheitis”, Virology 1995, p. 12-20, vol. 214.
Randall F. Smith et al., “Identification of New Protein Kinase-Related Genes in Three Herpesviruses, Herpes Simplex Virus, Varicella-Zoster Virus, and Epstein-Barr Virus”, Journal of Virology, Jan. 1989, p. 450-455, vol. 63, No. 1, American Society of Microbiology.
M. S. Chee et al., “Alpha-, Beta- and Gammaherpesviruses Encode a Putative Phosphotransferase”, J. gen. Virol., 1989, p. 1151-1160, vol. 70, Printed in Great Britain.
Guy Bradley et al., “Structure of the Marek's Disease Virus BamHI-H Gene Family: Genes of Putative Importance for Tumor Induction”, Journal of Virology, Jun. 1989, p. 2534-2542, vol. 63, No. 6, American Society for Microbiology.
Robert A. Crandell et al., “Development, Characterization, and Viral Susceptibility of a Feline (Felis Catus) Renal Cell Line (CRFK)”, In Vitro, 1973, p. 176-185, vol. 9, No. 3.
Takayuki Miyazawa et al., “Establishment of a feline T-lymphoblastoid cell line highly sensitive for replication of feline immunodeficiency virus”, Archives of Virology, 1989, p. 131-135, vol. 108.
Tsutomu Hohdatsu et al., “Comparative study of the cell tropism of feline immunodeficiency virus isolates of subtypes A, B and D classified on the basis of the env gene V3-V5 sequence”, Journal of General Virology, 1996, p. 93-100, vol. 77, Printed in Great Britain.
Paul A. Rota et al., “Physical Characterization of the Genome of Feline Herpesvirus-1”, Virology, 1986, p. 168-179, vol. 154.
A. Grail et al., “Restriction endonuclease mapping of the genome of feline herpesvirus type 1”, Archives of Virology, 1991, p. 209-220, vol. 116.
Niels De Wind et al., “Herpesviruses Encode an Unusual Protein-Serine/Threonine Kinase Which Is Nonessential for Growth in Cultured Cells”, Journal of Virology, Sep. 1992, p. 5200-5209, vol. 66, No. 9, American Society for Microbiology.
Marja J. Willemse et al., “Transcriptional Analysis of the Short Segment of the Feline Herpesvirus Type 1 Genome and Insertional Mutagenesis of a Unique Reading Frame”, Virology 208, 1995, vol. 208.
Kruger, J M et al., “Glycoproteins GL and gE of Feline Herpesvirus-1 Are Virulence Genes: Safety and Efficacy of a gl-gE-Deletion Mutant in the Natural Host”, Virology, Academic Press, Orlando, US, vol. 220, 1996, pp. 299-308.
Kawakami Kazuo
Kishi Masahiko
Mochizuki Masami
Kilpatrick & Stockton LLP
Kyoritsu Seiyaku Corporation
Li Bao Qun
Stucker Jeffrey
LandOfFree
Recombinant feline herpesvirus type 1 and polyvalent vaccine... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant feline herpesvirus type 1 and polyvalent vaccine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant feline herpesvirus type 1 and polyvalent vaccine... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4180944