Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-09-19
1999-07-27
Campell, Bruce R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
435 691, 4353201, 435325, 4352523, 536 232, 536 237, A61K 4800, C12N 510, C12N 1531, C12N 1563
Patent
active
059290455
ABSTRACT:
The invention provides MurD polypeptides and DNA (RNA) encoding MurD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurD polypeptides to screen for antibacterial compounds.
REFERENCES:
patent: 5681694 (1997-10-01), Hoskins et al.
Pucci, et. al., GenBank Submissiom, Accession No. U94707, "Identification and characterization of cell wall-cell division gene clusters in pathogenic gram-positive cocci."
Bertrand, et. al., "Crystal structure of UDP-N-acetyl muramoyle-L-analine: D-glutamate ligase from Escherichia coli." The EMBO Journal, vol. 16, No. 12, pp. 3416-3425, (1997).
Pratviel-Sosa, et. al., "Over-production, purification and properties of the uridine, diphosphate N-acetylmuramoyl-L-alanine: D-glutamate ligase from Escherichia coli." Eur. J. Biochem. vol. 202, pp. 1169-1176, (1991).
Itaya, et. al., "A new method for the colorimeter dtermination of inorganic phosphate." Clinical Chimica. Acta., vol. 14, pp. 361-366, (1966).
Fueyo Joanna Lynn
Lonetto Michael Arthur
Wallis Nicola Gail
Campell Bruce R.
Gimmi Edward R.
Jackson Arthur E.
King William T.
Priebe Scott D.
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