Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Patent
1994-10-14
1998-03-24
Guzo, David
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
4353201, C12N 701, C12N 1586
Patent
active
057311889
ABSTRACT:
The present invention relates to a non-naturally occurring, recombinant equine herpesvirus. The invention also relates to a recombinant equine herpesvirus capable of replication which comprises viral DNA from a species of equine herpesvirus and foreign DNA, the foreign DNA being inserted into the equine herpesviral DNA at a site which is not essential for replication of the equine herpesvirus. The invention also relates to DNA encoding the US2 protein of an equine herpesvirus. The invention relates to homology vectors for producing recombinant equine herpesviruses which produce recombinant equine herpesviruses by inserting foreign DNA into equine herpesviral DNA. The invention further relates to a method of producing a fetal-safe, live recombinant equine herpesvirus.
REFERENCES:
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Chiang Christina H.
Cochran Mark D.
Guzo David
Syntro Corporation
White John P.
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