Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2009-07-01
2010-12-14
Vogel, Nancy (Department: 1636)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C424S093600, C424S093100, C435S252500, C435S252300, C435S320100, C435S069100, C536S023100, C536S023720
Reexamination Certificate
active
07850958
ABSTRACT:
A recombinant double stranded RNA (dsRNA) nucleocapsid useful for the expression of dsRNA expression cassettes encoding passenger genes, such as, but not restricted to, vaccine antigens, bioactive proteins, immunoregulatory proteins, antisense RNAs, and catalytic RNAs, replicates in bacterial hosts and includes a P8 protein shell and three dsRNA segments where one of the segments includes a cap independent translation enhancer (CITE) operationally linked to a passenger gene.
REFERENCES:
patent: 7407790 (2008-08-01), Hone
patent: 2006/0115493 (2006-06-01), Hone et al.
Poranen, Virus Research, 2004, vol. 101, pp. 93-100.
Mindich et al., J. Bacteriology, 1999, vol. 181, No. 15, pp. 4505-4508.
Mindich, Microbiology and Molecular Biology Reviews, 1999, vol. 63, No. 1, pp. 149-160.
Hibbert Catherine
University of Maryland Biotechnology Institute
Vogel Nancy
Whitham Curtis Christofferson & Cook PC
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