Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Rodent cell – per se
Patent
1995-06-07
1998-10-27
Guzo, David
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Rodent cell, per se
4353201, 435375, 536 232, 536 235, C12N 510, C12N 1586, C07H 2104
Patent
active
058277390
ABSTRACT:
Recombinant DNA sequences which encode the complete amino acid sequence of a glutamine synthetase, vectors containing such sequences and methods for their use, in particular as dominant selectable markers, for use in co-amplification of non-selected genes and in transforming host cell lines to glutamine independence.
REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 4656134 (1987-04-01), Ringold
patent: 4797359 (1989-01-01), Finkelstein
patent: 5122464 (1992-06-01), Wilson et al.
Albert et al., Molecular Biology of the cell, Garland Publishing, Inc., New York, 1983. pp. 184-193.
Donn, Gunter et al., "Herbicide-Resistant Alfalfa Cells: An Example of Gene Amplification in Plants", Journal of Molecular and Applies Genetics, 2: 621-635 (1984).
Kaback, David B. et al., "Ribosomal DNA Magnification in Saccharomyces cerevisiae", Bacteriol, vol. 134, pp. 237-245 (1978).
Kaufman, Randal J. et al., "Selection and Amplification of Heterologous Genes . . . ", Proc.Natl.Acad.Sci.(USA), vol. 83, pp. 3136-3140 (1986).
Molecular Cloning, T. Maniatis et al., Cold Spring Harbor Laboratory, 1982, "Hybridization of DNA or RNA Immobilized on Filters to Radioactive Probes", pp. iii, iv, 324, 325, 382-389.
Murray, Mark J. et al., "Construction and use of a Dormant . . . ", Molec. and Cell Biol., vol. 3, No. 1, pp. 32-43 (1983).
Pennica, Diane et al., "Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli", Nature, vol. 301, pp. 214-221 (1983).
de Saint Vincent, Bruno Robert et al., "The Cloning and Reconstruction into Animal Cells of a Functional CAD Gene, a Dominant Amplifiable Genetic Marker", Cell, vol. 27, pp. 267-277 (1981).
Sanders, Peter G. et al., "Amplification and cloning of the Chinese Hamster glutamine synthetase gene", EMBO, vol. 3, No. 1, pp. 65-71 (1984).
Vel'Kov, V.V., "Amplification of Genes in Prokaryotic and Eukaryotic Systems", Soviet Genetics, vol. 18, pp. 348-396 (1982).
Watsen et al., Recombinat DNA, A Short Course, W.H. Freeman and Co., 1983. pp. 50-90.
Young, Anthony P. et al., "Mouse 3T6 Cells that Overproduce Glutamine Synthetase", The Journal of Biological Chmeistry, vol. 258, No. 18, pp. 11260-11266 (1983).
Bebbington Christopher Robert
Wilson Richard Harris
Celltech Therapeutics Limited
Guzo David
The University Court of the University of Glasgow
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