Recombinant DNA-produced T11 and fragments thereof

Details Recombinant DNA-produced T11 and fragments thereof Recombinant DNA-produced T11 and fragments thereof

1995-05-18

1997-03-04

Ziska, Suzanne E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

4351723, 935 1, 935 10, C12N 1500, C07K 1400

Patent

active

056080379

ABSTRACT:
A cDNA sequence encoding human T11 or a fragment thereof which is capable of inhibiting T-lymphocyte activation.

REFERENCES:
patent: 4381292 (1983-04-01), Bieber et al.
patent: 4810781 (1989-03-01), Hollinshead
Milanese, C., et al., "Clonal Analysis of B Cell Growth and Differentiation Activities Induced from T Lymphocytes Upon Triggering of T3-Ti and T11 Pathways," J. of Immunol., 135:1884-1890 (1985).
Rosenberg, S. A., et al., "Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer," N. E. J. of Med., 313:1485-1492 (1985).
Sewell, W. A., et al., "Molecular Cloning of the Human T-Lymphocyte Surface CD2 (T11) Antigen," Biochem. Soc. Trans., 14:1009 (1986).
Leca, G., et al., "The Sheep Erythrocyte Receptor and Both .alpha. and .beta. Chains of the Human T-Lympohocyte Antigen Receptor Bind the Mitogenic Lectin (Phytohaemagglutinin) from Phaseolus vulgaris, " Scand. J. Immunol., 23:535-544 (1986).
Sewell, W. A., et al., "Molecular Cloning of the Human T-Lymphocyte Surface CD2 (T11) Antigen," Proc. Natl. Acad. Sci. USA, 83:8718-8722 (1986).
Brown, M. H., et al., "Purification and N-terminal Amino Acid Sequence of the Human T Lymphocyte CD2 (T11) Surface Antigen," Eur. J. Immunol., 17:15-20 (1987).
Sayre, P. H., et al., "Molecular Cloning and Expression of T11 cDNAs Reveal a Receptor-Like Structure on Human T Lymphocytes," Proc. Natl. Acad. Sci. USA, 84:2941-2945 (1987).
Meuer, S. C., et al, "An Alternative Pathway of T-Cell Activation: A Functional Role for the 50 kd T11 Sheep Erythrocyte Receptor Protein," Cell, 36:897-906 (1984).
Palacios, R., and Martinez-Maza, O., "Is the E Receptor on Human T Lymphocytes a `Negative Signal Receptor`?" The Journal of Immunology, 129(6):2479-2485 (1982).
Treiger, B. F., et al, "A Secreted Form of the Human Interleukin 2 Receptor Encoded by an `Anchor Minus` cDNA," The Journal of Immunology, 136(11):4099-4105 (1986).
Rose, J. K., and Bergmann, J. E., "Expression from Cloned cDNA of Cell-Surface Secreted Forms of the Glycoprotein of Vesicular Stomatitis Virus in Eucaryotic Cells," Cell, 30:753-762 (1982).
Young, R. A., and Davis, R. W., "Efficient Isolation of Genes by Using Antibody Probes," Proc. Natl. Acad. Sci. USA, 80:1194-1198 (1983).
Siliciano, R. F., et al., "Activation of Cytolytic T Lymphocyte and Natural Killer Cell Function Through the T11 Sheep Erythrocyte Binding Protein," Nature, 317(3):428-430 (1985).
Fox, D. A., et al., "Regulation of the Alternative Pathway of T Cell Activation by Anti-T3 Monoclonal Antibody," The Journal of Immunology, 136(6):1945-1950 (1986).
Weiss, M. J., et al., "Calcium Dependency of Antigen-Specific (T3-Ti) and Alternative (T11) Pathways of Human T-Cell Activation," Proc. Natl. Acad. Sci. USA, 81:6836-6840 (1984).
Olive, D., et al., "Anti-CD2 (Sheep Red Blood Cell Receptor) Monoclonal Antibodies and T Cell Activation. I. Pairs of Anti-T11.1 and T11.2 (CD2 Subgroups) Are Strongly Mitogenic for T Cells in Presence of 12-O-Tetradecanoylphorbol 13-Acetate," Eur. J. Immunol., 16(9):1063-8 (1986). From Immunochemistry, 105:559 (1986), Abstract No. 189067c.
Meuer et al. vol. 36:897, 1984.
Palacios et al J of Immunol 129(6):2479, 1982.
Young et al PNAS 80:1194m 1983.
Rose et al Cell 30: 753, 1982.
Treiger et al J of Immunol. 136(11):4099, 1986.

Affiliated with

Also associated with

Rating

Recombinant DNA-produced T11 and fragments thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant DNA-produced T11 and fragments thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant DNA-produced T11 and fragments thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2146864