Recombinant DNA-produced T11 and fragments thereof

Details Recombinant DNA-produced T11 and fragments thereof Recombinant DNA-produced T11 and fragments thereof

1995-05-24

1996-08-27

Ziska, Suzanne E.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351723, 4353201, 435 691, 536 231, 536 235, 530350, C12N 1500, C12P 2106, C07K 1400, C07H 2104

Patent

active

055500552

ABSTRACT:
A cDNA sequence encoding human T11 or a fragment thereof which is capable of inhibiting T-lymphocyte activation.

REFERENCES:
patent: 4381292 (1983-04-01), Bieber et al.
patent: 4810781 (1989-03-01), Hollinshead
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Sewell, W. A., et al., "Molecular Cloning of the Human T-Lymphocyte Surface CD2(T11) Antigent," Biochem. Soc. Trans., 14:1009 (1986).
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Sewell, W. A., et al., "Molecular Cloning of the Human T-Lymphocyte Surface CD2 (T11) Antigen," Proc. Natl. Acad. Sci. USA, 83:8718-8722 (1986).
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Fox, D. A., et al., "Regulation of the Alternative Pathway of T Cell Activation by anti-T3 Monoclonal Antibody," The Journal of Immunology, 136(6):1945-1950 (1986).
Weiss, M. J. et al., "Calcium Dependency of Antigen-Specific (T3-Ti) and Alternative (T11) Pathways of Human T-Cell Activation," Proc. Natl. Acad. Sci. USA, 81:6836-6840 (1984).
Olive, D., et al., "Anti-CD2 (Sheep Red Blood Cell Receptor) Monoclonal Antibodies and T Cell Activation. I. Pairs of Anti-T11.1 and T11.2 (CD2 Subgroups) Are Strongly Mitogenic for T Cells in Presence of 12-O-Tetradecanoylphorbol 13-Acetate," Eur. J. Immunol., 16(9):1063-8 (1986). From Immunochemistry, 105:559 (1986), Abstract No. 189067c.

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