Recombinant DNA molecules

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 435 911, 435 6952, 4351723, 4353201, 4352523, 43525233, 536 2351, 536 2352, 514 2, 514 12, 935 4, 935 28, 935 37, 935 69, 935 11, C12P 2102, C12N 121, C12N 1570

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056020074

ABSTRACT:
This invention provides a DNA sequence coding for a mammalian granulocyte macrophage colony stimulating factor (GM-CSF), a method of obtaining same, vectors and hosts harboring same. The sequence is useful as a probe for identifying related sequences, selecting GM-CSF encoding mRNA from a mixture of mRNAs containing same, and a source of GM-CSF DNA for expression in an appropriate expression vector. The GM-CSF protein encoded by the sequence is useful for stimulating the production of granulocytes and macrophages from their respective progenitor cells.

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