Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide encodes an inhibitory rna molecule
Reexamination Certificate
2005-02-10
2010-12-21
Mehta, Ashwin (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
The polynucleotide encodes an inhibitory rna molecule
C435S320100
Reexamination Certificate
active
07855323
ABSTRACT:
Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
REFERENCES:
patent: 5107065 (1992-04-01), Shewmaker et al.
patent: 5231020 (1993-07-01), Jorgensen et al.
patent: 5283184 (1994-02-01), Jorgensen et al.
patent: 5508468 (1996-04-01), Lundquist et al.
patent: 5759829 (1998-06-01), Shewmaker et al.
patent: 6054299 (2000-04-01), Conrad
patent: 6054439 (2000-04-01), Szyf et al.
patent: 6090627 (2000-07-01), Kemp et al.
patent: 6160208 (2000-12-01), Lundquist et al.
patent: 6326193 (2001-12-01), Liu et al.
patent: 6326527 (2001-12-01), Kirihara et al.
patent: 6506559 (2003-01-01), Fire et al.
patent: 2002/0048814 (2002-04-01), Oeller
patent: 2003/0018993 (2003-01-01), Gutterson et al.
patent: 2003/0036197 (2003-02-01), Glassman et al.
patent: 2003/0175965 (2003-09-01), Lowe et al.
patent: 2004/0029283 (2004-02-01), Fillatti
patent: 2005/0176670 (2005-08-01), Huang et al.
patent: 2005/0193444 (2005-09-01), Malvar et al.
patent: 2005/0260754 (2005-11-01), Kock et al.
patent: 2006/0064772 (2006-03-01), Kriz et al.
patent: 0 428 881 (1991-05-01), None
patent: 0426195 (1991-05-01), None
patent: WO 98/26064 (1998-06-01), None
patent: WO 98/53083 (1998-11-01), None
patent: WO 99/49029 (1999-09-01), None
patent: WO 99/53050 (1999-10-01), None
patent: WO 99/53050 (1999-10-01), None
patent: WO 03/077643 (2003-09-01), None
patent: WO 03/078629 (2003-09-01), None
patent: WO 2005/077117 (2005-08-01), None
patent: WO 2005/077116 (2006-05-01), None
patent: WO 2007/024207 (2007-03-01), None
Chuang et al., PNAS, 2000, vol. 97, pp. 4985-4990).
Redenbaugh et al., “Safety Assessment of Genetically Engineered Flave Savr TM Tomato”, CRC Press, Inc (1992) pp. 88-102.
Slam et al., The Plant Journal, 12:63-82 (1997).
DeBuck et al., Plant Mol.Biol., 46:433-445 (2001).
Sijen et al., The Plant Cell, 8:2277-2294 (1996).
Jorgensen et al., Mol.Gen. Genet., 207:471-477 (1987).
Mette et al., The EMBO Journal, 18:241-248 (1999).
Mette et al., The EMBO Journal, 19:5194-5201 (2000).
Sanders et al., “Tomato transgene structure and silencing”, Nature Biotechnology, 23:3:287-289 (Mar. 2005).
Smith et al., Total Silencing by intron-spliced hairpin RNAs (Nature), Sep. 21, 2000, vol. 407, pp. 319-320, see whole document.
Waterhouse et al, Virus Resistance and gene silencing in plants . . . (Proc. Natl. Acad. Sci. USA), Nov. 1998, vol. 95, pp. 1359-1364.
Wesley et al., Construct Design for efficient, effective and high through-put gene silencing in plants, (Plant J.) 2001, vol. 27 ,pp. 581-590.
Anonymous, “About CSIRO's hairpin RNAi,” Retrieved from the Internet, http:.//www.p1.csiro.au/rnai/about.htm, Sep. 15, 2005.
Huang et al., “High lysine and high tryptophan transgenic maize resulting from the reduction of both 19- and 22-kD alpha-zeins,”Plant Molecular Biology, 61(3):525-535, 2006.
Rebowski et al., “Antisense hairpin loop oligonucleotides as inhibitors of expression of multidrug resistance-associated protein 1: their stability in fetal calf serum and human plasma,”ACTA Biochimica Polonica, 48(4):1061-1076, 2001.
Supplemental European Search Report dated Jul. 21, 2008.
Houmard et al., “High-lycine corn generated by endosperm-specific suppression of lysine catabolism using RNAi,”Plant Biotechnology J., 5:605-614, 2007.
Alvarez et al., “Crabs Claw and Spatula, two arabidopsis genes that control carpel development in parallel with AGAMOUS,”Development, 126:2377-2386, 1999.
Chuang et al., “The PERIANTHIA gene encodes a bZIP protein involved in the determination of floral organ number in arabidopsis thaliana,”Genes & Devel., 13:334-344, 1999.
Amendment and Response to Office Action regarding U.S. Appl. No. 11/202,401, dated Jun. 23, 2008.
Helliwell et al., “High-throughput vectors for efficient gene silencing in plants ,”Funct. Plant Biol., 29:1217-1225, 2002.
Huang et al., “High-lysine corn produced by the combination of enhanced lysine biosynthesis and reduced zein accumulation,”Plant Biotechnology Journal, 3:555-569, 2005.
Huang et al., “Improving nutritional quality of maize proteins by expressing sense and antisense zein genes,”J. Agric. Food Chem., 52:1958-1964, 2004.
Office Action regarding U.S. Appl. No. 11/202,401, dated Feb. 21, 2008.
Office Action regarding U.S. Appl. No. 11/202,401, dated Sep. 30, 2008.
Redenbaugh et al., “Aminoglycoside 3′-phosphototransferase-II (APH) (3′)II)—review of its safety and use in the production of genetically-engineered plants,”Food Biotechnology, 8(2-3):137-165, 1994.
Redenbaugh et al., “Determination of the safety of genetically engineered crops,” ACS Symposium Series 605:72-87, 1995.
Redenbaugh et al., “Regulatory assessment of the flavr-savr tomato,”Trends in Food Science&Technology, 5(4):105-110, 1994.
Redenbaugh et al., “Regulatory issues for commercialization of tomatoes with an antisense polygalacturonase gene,”In Vitro Cellular&Developmental Biology—Plant; 29P(1):17-26, 1993.
Russell et al., “Tissue-specific expression in transgenic maize of four endosperm promoters from maize and riceZein Z27,”Transgenic Res., 6(2):157-168, 1997.
Segal et al., “A new opaque variant of maize by a single dominant RNA-interference-inducing transgene,”Genetics, 165:387-397, 2003.
Unger et al., “Dominant negative mutants of opaque2 suppress transactivation of a 22-kD zein promoter by opaque2 in maize endosperm cells,”The Plant Cell, 5:831-841, 1993.
Huang Shihshieh
Luethy Michael H.
Malvar Thomas M.
McBride, Esq. Thomas P.
Mehta Ashwin
Monsanto Technology LLC
SNR Denton US LLP
LandOfFree
Recombinant DNA for gene suppression does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant DNA for gene suppression, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant DNA for gene suppression will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4181655