Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1988-05-09
1991-12-03
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
43525233, 43525235, 435254, 435255, 4351723, 4353201, 536 27, C12N 1563, C12N 1552, C12N 1580, C12N 1576
Patent
active
050700200
ABSTRACT:
The present invention provides DNA compounds that encode deacetoxycephalosporin C synthetase (DAOCS) activity. The compounds can be used to construct recombinant DNA expression vectors for a wide variety of host cells, including E. coli, Penicillium, Streptomyces, Aspergillus, and Cephalosporium.
REFERENCES:
patent: 4510246 (1985-04-01), Wolfe et al.
patent: 4536476 (1985-08-01), Wolfe et al.
Jensen et al., Sep. 1983, Antimicrobial Agents and Chemotherapy 24(3):307.
Jensen et al., Feb. 1985, The Journal of Antibiotics XXXVIII(2):263.
Samson et al., 1987, Bio/Technology 5(11).
Ingolia Thomas D.
Kovacevic Steven
Miller James R.
Skatrud Paul L.
Eli Lilly and Company
Hamilton Amy E.
Nolan S. L.
Schwartz Richard A.
Whitaker Leroy
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