Recombinant DNA expression vector comprising both transcriptiona

Details Recombinant DNA expression vector comprising both transcriptiona Recombinant DNA expression vector comprising both transcriptiona

1989-12-12

1991-11-05

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4351723, 43525233, 4353201, 536 27, 935 33, 935 39, 935 44, C12N 1567, C12N 1509, C07N 1512

Patent

active

050631586

ABSTRACT:
The present invention is composed of novel recombinant DNA expression vectors which contain a transcriptional activating sequence, a translational activating sequence and a DNA sequence coding for a functional polypeptide, especially bovine growth hormone. The aforementioned translational activating sequences contain a ribosome binding site and are designed to provide high level expression of DNA that codes for virtually any functional polypeptide. The invention further provides transformed microbial host cells capable of producing bovine growth hormone and other functional polypeptides at high levels.

REFERENCES:
patent: 4693973 (1987-10-01), Buell et al.
patent: 4806471 (1989-02-01), Molin et al.
Miller et al., 1980, The Journal of Biological Chemistry, 255(16):7521.
Martial et al., 1979, Science 205:602.
Seeburg et al., 1983, DNA 2(1):37.
Masiu et al., The International Journal of Biology and Industry, Jan. 1984:81.
Movva et al., 1980, Proceedings of the National Academy of Science 77(7):3845.
Schoner et al., 1984, Proceedings of the National Academy of Science 81:5403.
Iserentant et al., 1980, Gene, 9:1.
Jay et al., 1981, Proc. Natl. Acad. Sci. U.S.A. 78(9):5543.
Shepard et al., 1982, DNA 2(s):125.
Gheysen et al., 1982, Gene, 17:55.
Kastelein et al., 1983, Gene, 23:245.
Hui et al., 1984, The EMBO Journal, 3(3):623.
Tessier et al., 1984, Nucleic Acids Research, 12(20):7663.
Stanssens et al., 1985, Gene, 36:211.
Marquis et al., 1986, Gene, 42:175.

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