Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1988-03-07
1990-08-21
Wiseman, Thomas G.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530403, 530825, 530300, 514 2, 424 88, 4351721, 4351723, 935 10, 935 12, C07K 1300, C07K 700
Patent
active
049507400
ABSTRACT:
Recombinant diphtheria toxin A fragment muteins which are enzymatically inactive but immunologically crossreactive with diphtheria toxin are disclosed. Intermediates and methods for preparing such proteins using recombinant techniques are also described.
REFERENCES:
patent: 4709017 (1987-11-01), Collier et al.
Carroll et al., PNAS 81: 3307-3311.
Anderson et al., Infect. & Immunity, 39: 233-238.
Giannini (1984), NAC 12: 4063-4069.
Kaczorek (1983), Science 226: 855-858.
Uchida et al. (1983), J.B.C. 248: 3851-3857.
Greenfield et al. (1987), PNAS 80: 6853-6857.
Emerick Anne W.
Greenfield Lawrence
Laird Walter J.
Brown Anne
Cetus Corporation
Giotta Gregory J.
Halluin Albert P.
Murashige Kate H.
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