Recombinant diphtheria toxin fragments

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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4351723, 435320, 43525233, 43525231, 43525234, 536 27, C12P 2100, C12N 1500, C12N 120

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active

048309621

ABSTRACT:
Recombinant vectors which are effective in expressing DNA sequences encoding specific fragments of diphtheria toxins at high levels in recombinant host cells are disclosed. Both a fragment consisting of the enzymatically active A chain of diphtheria toxin and a fragment consisting of both the A portion and a B portion partial sequence are constructed by use of this recombinant vector.

REFERENCES:
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