Recombinant deoxyribonucleic acid which codes for plasminogen ac

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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536 28, 536 29, C12P 2100

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045580103

ABSTRACT:
The present invention provides a deoxyribonucleic acid (DNA) segment related to a human plasminogen activator gene. The segment is inserted into a plasmid vector which in turn can be incorporated into a bacterium or other microorganism. The bacterium can then be cultured to produce a plasminogen activator protein having properties of human urokinase.

REFERENCES:
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patent: 4190649 (1980-02-01), Beljanski
patent: 4237224 (1980-12-01), Cohen
patent: 4335239 (1982-06-01), Beljanski
Chang, et al., Nature, vol. 275, 617-622, (Oct. 1978).

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