Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Patent
1995-07-20
2000-06-13
Campell, Bruce R.
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
4353201, 435325, 536 231, C07H 2104, C12N 1585, C12N 700, C12N 1500
Patent
active
060748656
ABSTRACT:
A recombinant protein encompassing the complete envelope glycoprotein and a portion of the carboxy-terminus of the membrane/premembrane protein of dengue 2 virus was expressed in baculovirus as a protein particle. The recombinant protein particle was purified and found to provide protection against lethal challenge with dengue 2 virus in mice.
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Delenda et al. Analysis of C-terminally truncated denuge 2 and dengue 3 virus envelope glycoproteins: processing in insect cells and immunogenic properties in mice. J. Gen. Virol. 75: 1569-1578, 1994.
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Kelly Eileen P.
King Alan D.
Campell Bruce R.
Clark Deborah J. R.
Harris Charles H.
Moran John Francis
The United States of America as represented by the Secretary of
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