Recombinant cytomegalovirus vaccine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...

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4241861, 4242307, 4242331, 4242781, 435 691, 435 693, 4351723, 4352351, 536 231, 536 2372, A61K 39295, A61K 39245, A61K 39235

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055521436

ABSTRACT:
The present invention provides a non-defective adenovirus recombinant expression system for the expression of the HCMV gB subunit, an immunogenic fragment of the gB subunit, and for the expression of non-structural immediate-early exon 4 proteins, said recombinant HCMV-expressing adenovirus being useful as a vaccine.

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