Recombinant coryneform bacterium for producing L-tryptophan

Details Recombinant coryneform bacterium for producing L-tryptophan Recombinant coryneform bacterium for producing L-tryptophan

1990-05-30

1995-04-18

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435108, 435183, 4351723, 4353201, 536 231, 536 232, 536 237, C12N 121, C12N 1577

Patent

active

054078245

ABSTRACT:
L-tryptophan is produced by constructing a recombinant DNA composed of a vector DNA and DNA fragments bearing all of genetic information relating to the synthesis of DS, AS, PRT, PRAI, InGPS, TS and PGDH, introducing the recombinant DNA into a microorganism belonging to the genus Corynebacterium or Brevibacterium, culturing the microorganism in a medium, and recovering L-tryptophan accumulated in the culture.

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Ikeda, et al., Improved Tryptophan (trp) Producing Microorganism Corynebacterium glutamicum, J. Japan Agr. Chem. Assoc., 63(3) p. 701 (1989).
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Patent Abstracts of Japan, vol. 10, No. 345 (C-386) [2401], Nov. 20, 1986.
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Matsui et al., 1988, Agric. Biol. Chem., 52(7): 1863-1865.
Somerville, 1983, In: Amino Acids; Biosynthesis and Regulation, Addison-Wesley, Helmann et al. (eds), pp. 351-361.
Stauffer, 1983, In: Amino Acids: Biosynthesis and Regulation, Addison-Wesley, Hermann et al. (eds), pp. 103-113.

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