Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2006-06-28
2008-11-25
McGarry, Sean R (Department: 1635)
Chemistry: molecular biology and microbiology
Vector, per se
C536S023100, C536S024100, C536S024500, C435S006120
Reexamination Certificate
active
07456014
ABSTRACT:
Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.
REFERENCES:
patent: 4945050 (1990-07-01), Sanford et al.
patent: 5107065 (1992-04-01), Shewmaker et al.
patent: 5231020 (1993-07-01), Jorgensen et al.
patent: 5510474 (1996-04-01), Quail et al.
patent: 5591616 (1997-01-01), Hiei et al.
patent: 5614399 (1997-03-01), Quail et al.
patent: 5648210 (1997-07-01), Kerr et al.
patent: 5683439 (1997-11-01), Jensen
patent: 5689049 (1997-11-01), Cigan et al.
patent: 5689051 (1997-11-01), Cigan et al.
patent: 5773699 (1998-06-01), Kerr et al.
patent: 5942657 (1999-08-01), Bird et al.
patent: WO 93/11245 (1993-06-01), None
patent: WO 93/23551 (1993-11-01), None
patent: WO 94/11516 (1994-05-01), None
patent: WO 97/47731 (1997-12-01), None
patent: WO 98/30701 (1998-07-01), None
patent: WO 98/36083 (1998-08-01), None
patent: WO 98/50553 (1998-11-01), None
patent: WO 99/15682 (1999-04-01), None
patent: WO 99/32619 (1999-07-01), None
patent: WO 99/53050 (1999-10-01), None
patent: WO 00/09706 (2000-02-01), None
patent: WO 00/11176 (2000-03-01), None
patent: WO 00/11177 (2000-03-01), None
patent: WO 00/12733 (2000-03-01), None
patent: WO 01/77306 (2001-10-01), None
Carolyn Napoli et. al., The Plant Cell, vol. 2:279-289, 1990, Introduction of a Chimeric Chalcone Synthase Gene Into Petunia Results in Reversible Co-Suppression of Homologous Genes in Trans.
Herve Vaucheret et. al., The Plant Journal, vol. 16:651-659, 1998, Transgene-Induced Gene Silencing in Plants.
Trisha Gura,, Nature, vol. 404:804-808, 2000, A Silence That Speaks Volumes.
Mary K. Montgomery et. al., TIG, vol. 14:255-258, 1998, Double-Stranded RNA as a Mediator in Sequence-Specific Genetic Silencing and Co-Suppression.
Andrew Fire et. al., Nature, vol. 391:806-811, 1998, Potent and Specific Genetic Interference by Double-Stranded RNA inCaenorhabditis elegans.
Scott M. Hammond et. al., Nature, vol. 404:293-296, 2000, An RNA-Directed Nuclease Mediates Post-Transcriptional Gene Silencing inDrosophilaCells.
Nicoletta Romano et. al., Molecular Microbiology, vol. 6:3343-3353, 1992, Quelling: Transient Inactivation of Gene Expression inNeurospora crassaby Transformation With Homologous Sequences.
Sarah R. Grant, Cell, vol. 96:303-306, 1999, Dissecting the Mechanisms of Posttranscriptional Gene Silencing: Divide and Conquer.
David C. Baulcombe, The Plant Cell, vol. 8:1833-1844, 1996, Mechanisms of Pathogen-Derived Resistance to Viruses in Transgenic Plants.
Eric U. Selker, Cell, vol. 97:157-160, 1999, Gene Silencing: Repeats That Count.
Jack K. Okamuro et al., Biochemiistry of Plants, vol. 15:-182, 1989, Regulation of Plant Gene Expression: General Principles.
Roisin Turner et al., Molecular Biotechnology, vol. 3:225-236, 1995, The Potential Exploitation of Plant Viral Translational Enhancers in Biotechnology for Increased Gene Expression.
Ivan L. W. Ingelbrect et al., The Plant Cell, vol. 1:671-680, 1989, Different 3'End Regions Strongly Influence the Level of Gene Expression in Plant Cells.
T. M. Klein et al., Nature, vol. 327:70-73, 1987, High-Velocity Microprojectiles for Delivering Nucleic Acids Into Living Cells.
Yuji Ishida et al., Nature Biotech., vol. 14:745-750, 1996, High Efficiency Transformation of Maize (Zea Mays L.) Mediated byAgrobacterium tumefaciens.
Jonathan D. G. Jones et al., The EMBO Journal, vol. 4:2411-2418, 1985, High Level Expression of Introduced Chimeric Genes in Regenerated Transformed Plants.
Eleanor P. De Almeida et al., Mol. Gen. Genet., vol. 218:78-86, 1989, Transgenic Expression of Two Marker Genes Under the Control of an Arabidopsis RBCS Promoter.
Taline Elmayan et al., The Plant Cell, vol. 10:1747-1757, 1998, Arabidopsis Mutants Impaired in Cosuppression.
T. J. V. Higgins, Ann. Rev. Plant Phys., vol. 35:191-221, 1984, Synthesis and Regulation of Major Proteins in Seeds.
Champa Sengupta-Gopalan et al., PNAS, vol. 82:3320-3324, 1985, Developmentally Regulated Expression of the Bean-B-Phaseolin Gene in Tobacco Seed.
Leslie M. Hoffman et al., Plant Mol. Biol., vol. 11:717-729, 1988, A Modified Storage Protein is Synthesized, Processed, and Degraded in the Seeds of Transgenic Plants.
Toni Voelker et al., The EMBO Journal, vol. 6:3571-3577, 1987, Differences in Expression Between Two Seed Lectin Alleles Obtained From Normal and Lectin-Deficient Beans are Maintained in Transgenic Tobacco.
Jack K. Okamuro et. al., Proc. Natl. Acad. Sci. USA, vol. 83:8240-8244, 1986, Soybean Seed Lectin Gene and Flanking Nonseed Protein Genes are Developmentally Regulated in Transformed Tobacco Plants.
Luis Perez-Grau et. al., The Plant Cell, vol. 1:1095-1109, 1989, Soybean Seed Protein Genes are Regulated Spatially During Embryogenesis.
R. N. Beachy et. al., The EMBO Journal, vol. 4:3047-3053, 1985, Accumulation and Assembly of Soybean B-Conglycinin in Seeds of Transformed Petunia Plants.
Thomas J. V. Higgins et. al., Plant Molecular Biology, vol. 11:683-695, 1988, The Sequence of a Pea Vicilin Gene and its Expression in Transgenic Tobacco Plants.
Edward J. Newbigin et. al, Planta, vol. 180:461-470, 1990, Pea Convicilin: Structure and Primary Sequence of the Protein and Expression of a Gene in the Seeds of Transgenic Tobacco.
Anil Shirsat et. al., Mol. Gen. Genet., vol. 215:326-331, 1989, Sequences Responsible for the Tissue Specific Prometer Activity of a Pea Legumin Gene in Tobacco.
Leslie M. Hoffman et. al., The EMBO Journal, vol. 6:3213-3221, 1987, Synthesis and Protein Body Deposition of Maize 15-KD Zein in Transgenic Tobacco Seeds.
Woo S. Lee et. al., Proc. Natl. Acad. Sci. USA, vol. 88:6181-6185, 1991, Maize Oleosin is Correctly Targeted to Seed Oil Bodies inBrassica napusTransformed With the Maize Oleosin Gene.
Claire Marris et. al., Plant Molecular Biology, vol. 10:359-366, 1988, The 5′ Flanking of a Barley B Hordein Gene Controls Tissue and Development Specific CAT Expression in Tobacco Plants.
V. Colot et. al., The EMBO Journal, vol. 6:3559-3564, 1987, Localization of Sequences in Wheat Endosperm Protein Genes Which Confer Tissue-Specifc Expression in Tobacco-.
Joel Vandekerckhove et. al., Bio/Technology, vol. 7:929-932, 1989, Enkephalins Produced in Transgenic Plants Using Modified 2S Seed Storage Proteins.
Daniel Riggs et. al., Plant Science, vol. 63:47-57, 1989, Utilization of Luciferase Fusion Genes to Monitor Differential Regulation of Phytohemagglutinin and Phaseolin Promoters in Transgenic Tobacco.
A. Boronat et. al., Plant Science, vol. 47:95-102, 1986, Isolation and Sequencing of a 28 KD Glutelin-2 From Maize. Common Elements in the 5′ Flanking Regions Among Zein and Glutelin Genes.
M. Reina et. al., Nucleic Acids Research, vol. 18:6426, 1990, Sequence Analysis of a Genomic Clone Encoding a ZC2 Protein From Zea Mays W64 A.
Ralf Bernd Klosgen et. al., Mol. Gen. Genet., vol. 203:237-244, 1986, Molecular Analysis of the Waxy Locus of Zea Mays.
Alan H. Christensen et. al., Plant Molecular Biology, vol. 12:619-632, 1989, Sequence Analysis and Transcriptional Regulation by Heat Shock of Polyubiquitin Transcripts From Maize.
Gynheung An et. al., The Plant Cell, vol. 1:115-122, 1989, Functional Analysis of the 3′ Control Region of the Potato Wound-Inducible Proteinase Inhibitor II Gene.
Richard A. Jefferson et. al., Proc. Natl. Acad. Sci. USA, vol. 83:8447-8451, 1986, B-Glucuronidase FromEscherichia colias a Gene-Fusion Marker.
Stephen F. Altschul et. al., J. Mol. Biol., vol. 215:403-410, 1990, Basic Local Alignment Search Tool.
Warren Gish et. al., Nature Genet., vol. 3:266-272, 1993, Identification of Protein Coding Regions by Database Similarity Search.
E. Cristofaro et. al., In Sugars in Nutrition, Chapter 20:313-335, 1974, Involvement of the Raffinose Family of Oligosaccharides in Flatulence.
P. M. Dey, In Biochemistry of Storage Ca
Kinney Anthony J.
Stecca Kevin L.
E. I. du Pont de Nemours and Company
McGarry Sean R
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