Recombinant Brucella abortus gene expressing immunogenic protein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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4353171, 4353201, 536 27, C12P 634, C12N 1500, C07H 1512

Patent

active

050231740

ABSTRACT:
A gene of Brucella abortus encoding a novel 31,000 dalton immunogenic protein has been isolated and introduced into synthetic recombinant DNA molecules. A plasmid containing the gene sequence also contains a promoter sequence for expression of the gene.

REFERENCES:
patent: 4464473 (1984-08-01), Orser et al.
patent: 4468464 (1984-08-01), Cohen et al.
Verstreate et al., 1984, Infec. and Immun. 46, 182-187.
Winter et al., 1983 Infec. and Immun. 42, 1159-1167.
Bolivar F., 1978 Gene 4, 121-136.

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