Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Hormone or other secreted growth regulatory factor,...
Patent
1994-06-21
1998-03-31
Feisee, Lila
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Hormone or other secreted growth regulatory factor,...
4241991, 4242271, 435 691, 435 693, A61K 3900
Patent
active
057335532
ABSTRACT:
A recombinant birth control vaccine comprising a beta subunit of chorionic gonadotropin, a recombinant luteinizing hormone or a mixture thereof has been developed. This recombinant birth control vaccine may also act as a vaccine against a protein or peptide unassociated with the mammalian reproductive system, such as a protein or peptide associated with a disease organism such as hepatitis B.
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patent: 4780312 (1988-10-01), Talwar
patent: 4847080 (1989-07-01), Neurath et al.
Talwar et al., "Recent developments in immunocontraception" American Journal of Obstetrics and Gynecology (1987) 157:1075-1078.
Lall et al., "Recombinant vaccinia virus express immunoreactive alpha subunit of ovine luteinizing hormone which associates with .beta.-hCG to generate bioactive dimer" Indian Journal of Biochemistry & Biophysics (1988) 25:510-514.
Edwards, Rg. Conception in the Human Female, pp. 200-201, 1980, Academic Press.
Niles, E.D., et al., "Vaccinia virus gene D8 encodes a virion transmembrane protein" J. Viol. (1988) 62(10):3772-3778.
Chakrabarti, S., et al., "Expression of biologically active human chorionic gonadotropin and its subunits by recombinant vaccinia virus" Gene (1989) 77:89-93.
Smith, G.L., et al., "Infectious vaccinia virus recombinants that express hepatitis B virus surface antigen"Nature (1983) 302:490-495.
Chakrabarti Sekhar
Srinivasan Jay
Talwar Gursaran Prasad
Feisee Lila
Reeves Julie E.
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