Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-03-28
2006-03-28
Wax, Robert A. (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S827000
Reexamination Certificate
active
07019114
ABSTRACT:
The invention relates to methods for producing recombinant human zona pellucida protein (“rhZP3”) and glycosylated peptide having biological activity of binding to human spermatozoa. A human ovarian cell line is used to produce rhZP3 having a glycosylation pattern required for full biological activity. Methods of determining useful peptides with binding activity for human sperm and their syntheses, as well as using such peptides and proteins in therapeutics and diagnostics are discussed.
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Was
Dong Ke-Wen
Gibbons William E.
Oehninger Sergio
Eastern Virginia Medical School
Mayer Suzanne M.
Wax Robert A.
Wilmer Cutler Pickering Hale and Dorr LLP
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