Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-05-03
2005-05-03
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S320100, C435S069100, C435S325000, C435S348000, C435S252300, C435S007100, C435S254110, C536S023100, C536S023200, C536S023500, C536S024100, C536S024300
Reexamination Certificate
active
06887661
ABSTRACT:
Promising groups of environmetally-safe insecticides consist of analogues of insect hormones, such as juvenile hormone, and antagonists of such hormones. The traditional bioassay approach for screening potential juvenile hormone analogs and antagonists is slow, expensive and inefficient. A recombinant bHLH-PAS-juvenile hormone receptor, isolated from the methoprene-tolerant locus onDrosophila, provides the basis of in vitro and in vivo binding assays that can be used to discover new juvenile hormone-type targeted insecticides. Moreover, the nucleotide sequence of theDrosophilabHLH-PAS/JHR polypeptide provides tools for isolating juvenile hormone receptor genes from other insect species.
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Heinrich Julia N.
Wilson Thomas G.
American Cyanamid Company
Colorado State University Research Foundation
Guzo David
Sutherland & Asbill & Brennan LLP
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