Recombinant avipoxvirus

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

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424 89, 4351723, 4353201, 935 65, C12N 701, C12N 1586, A61K 39275, A61K 39295

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052866394

ABSTRACT:
A recombinant Avipoxvirus having inserted all or a part of cDNA coding for Newcastle disease virus-derived hemagglutinin neuraminidase in a genome region non-essential to proliferation of Avipoxvirus is provided. The recombinant Avipoxvirus is utilizable as vaccine for fowl.

REFERENCES:
patent: 4603112 (1986-07-01), Paoletti
Jorgensen, C.A. 107:169718d, "Cloning, nucleotide sequence, and expression the Newcastle disease virus hemagglutinin-neuraminidase glycoprotein gene" (1987).
Wemers, C.A. 108:125379k, "The hemagglutinin-neuraminidase (HN) gene of Newcastle disease virus strain Italien (ndv Italien): comparison with HNs of other strains and expression by a vacciniarecombinant" (1988).
Chakrabati et al., (1986) from "Vaccines 86, New Approaches in Immunology", Ed. F. Brown et al, Cold Spring Harbor Laboratory, p. 2-292.
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Adine D. F. 1980 "A Pilot Study of the Potency of a Combined Newcastle Fowl Pox", Dialog Accession #542968.

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