Recombinant avipox virus and immunological use thereof

Details Recombinant avipox virus and immunological use thereof Recombinant avipox virus and immunological use thereof

1990-06-14

1992-12-29

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Lymphokine

4352351, 4353201, 424 93, 935 32, 935 57, 935 65, A61K 39295, A61K 39275, C12N 701, C12N 1586

Patent

active

051749939

ABSTRACT:
The present invention provides a method for inducing an immunological response in a vertebrate to a pathogen by inoculating the vertebrate with a synthetic recombinant avipox virus modified by the presence, in a non-essential region of the avipox genome, of DNA from any source which codes for and expresses an antigen of the pathogen. The present invention further provides a synthetic recombinant avipox virus modified by the insertion therein of DNA from any source, and particularly from a non-avipox source, into a non-essential region of the avipox genome.

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